辛伐他汀治疗不稳定型心绞痛疗效评价  

Evaluation of effectiveness of simvastatin injection in the treatment of unstable angina pectoris

作　　者：王飞鸣[1] 孙红军[1] 李科民[1] 陈向民[1] 梅廷方[1] 

机构地区：[1]安徽省蚌埠市第一人民医院心血管内科,233000

出　　处：《淮海医药》2009年第5期401-402,共2页Journal of Huaihai Medicine

摘　　要：目的评价辛伐他汀治疗不稳定型心绞痛的疗效。方法将60例患者随机分为对照组和治疗组。观察比较2组心绞痛缓解时间,心电图及低密度脂蛋白胆固醇在治疗前后的变化。结果2组心绞痛疗效比较,治疗组总有效率96%,对照组总有效率80%,差异有统计学意义(P<0.05);低密度脂蛋白胆固醇在治疗后[2.26±1.99)mmol/L]与对照组治疗后[3.25±1.03)mmol/L]相比差异有非常显著性,(P<0.01)。结论辛伐他汀治疗不稳定型心绞痛有较好郊效。Objective To evaluate the effectiveness of simvastatin in the treatment of unstable angina pectoris. Methods 60 patients were randomly divided into a control group and a treatment group to compare the alleviation time, change of ECG and LDL-C before and after the therapy. Results Compared statistically, LDL-C in the treatment group （ 2.26 ± 1.99mmol/ L） and in the eontrol group（3.25 ± 1.03mmol/L） after the therapy was significantly different （P 〈 0.01 ）. Of the two groups, the effectiveness of angina relief in the treatment group was 96% compared with 80% in the control group. There were significant differenees（ P 〈 0.05 ）. Conclusion Simvastatin plays an important role in the treatment of unstable pectoris angina.

关 键 词：心绞痛 不稳定型 辛伐他汀 治疗结果 

分 类 号：R541.42[医药卫生—心血管疾病]