酚酞分子印迹聚合物的制备及其特异吸附性能  

Preparation and Specific Adsorption Performance of Molecularly Imprinting Polymers for Phenolphthalein

作　　者：石慧丽[1] 樊静[1] 魏娅方[1] 

机构地区：[1]河南师范大学化学与环境科学学院,黄淮水环境与污染防治省部共建教育部重点实验室,河南省环境污染控制重点实验室,新乡453007

出　　处：《应用化学》2009年第8期971-975,共5页Chinese Journal of Applied Chemistry

基　　金：河南省基础与前沿技术研究计划项目(082300423202)

摘　　要：以泻药酚酞为模板分子,4-乙烯基吡啶为功能单体制备了模板分子和功能单体不同比例的一系列酚酞分子印迹聚合物。采用扫描电子显微镜对聚合物进行了表面形态分析,用静态平衡法研究了聚合物对模板分子及其类似物的吸附行为和选择性识别能力。结果表明,所制备的分子印迹聚合物吸附3 h后基本达到最大吸附量,其中n(模板分子)∶n(4-乙烯基吡啶)∶n(交联剂)=1∶6∶20时MIP的印迹因子为2.30,效果最佳。Scatchard分析表明,在所研究的浓度范围内,吸附过程存在高低亲和力2类结合位点,其离解常数分别为Kd1=0.63 mmol/L和Kd2=3.5 mmol/L,最大表观结合量分别为Qmax1=25.4μmol/g和Qmax2=61.9μmol/g,通过与酚酞类似物质在酚酞分子印迹聚合物上吸附行为比较,表明MIP对酚酞具有很好的选择性吸附。A series of molecularly imprinting polymers（MIPs） at different ratios of template to functional monomer were prepared with phenolphthalein as the template and 4-vinylpyridine as the functional monomer.The surface features of the polymers were analyzed by scanning electron micrography.The static equilibrium binding experiments were performed to investigate the adsorption property and selective recognition of the MIPs for phenolphthalein and its analogues.It showed that the saturated adsorption was achieved in 3 h.The best imprinting effect was observed when the molar ratio of the template molecules,functional monomer and crosslinker was 1∶6∶20.Scatchard analysis shows that two classes of binding sites were formed in the imprinted polymers in the concentrations range studied.The calculated dissociation constant Kd1 and the apparent maximum binding capacities Qmax1 for the high affinity sites are 0.63 mmol/L and 25.4 μmol/g,while Kd2 and Qmax2 for the low affinity sites are 3.5 mmol/L and. 61.9 μmol/g,respectively.The molecularly imprinting polymers display a higher selectivity for phenolphthalein compared with the analogues of phenolphthalein.

关 键 词：酚酞 分子印迹聚合物 制备 特异吸附 

分 类 号：O631[理学—高分子化学]