福建省不同疫区肾综合征出血热宿主动物监测及病毒分离  

Surveillance and isolation virus of hemorrhagic fever with renal syndrome at different epidemic areas in Fujian

作　　者：陈阳[1] 何似[1] 李世清[1] 林代华[1] 李述杨[1] 周淑姮[1] 陈亮[1] 王灵岚[1] 

机构地区：[1]福建省疾病预防控制中心自然疫源性疾病防治科,福州350001

出　　处：《中国媒介生物学及控制杂志》2009年第4期352-354,共3页Chinese Journal of Vector Biology and Control

摘　　要：目的了解福建省肾综合征出血热(HFRS)疫区类型,为防治工作提供依据。方法应用笼夜法捕鼠,计算鼠密度及鼠种构成,对鼠肺进行HFRS病毒抗原检测及病毒分离与鉴定。结果家鼠型疫区室内平均鼠密度为4.91%,褐家鼠为主要鼠种。混合型疫区室内平均鼠密度为5.73%,褐家鼠为优势种;野外平均鼠密度为12.95%,秋冬季明显高于春季,黑线姬鼠为优势种。室内以褐家鼠为主要带病毒鼠种,携带Ⅱ型病毒,野外带病毒鼠均为黑线姬鼠,携带Ⅰ型病毒。从黑线姬鼠和褐家鼠中各分离出1株HFRS病毒,定名为A44和R50株。结论福建省HFRS的主要宿主动物仍以褐家鼠为主,混合型疫区野外主要宿主动物为黑线姬鼠,应加强重点疫区和老疫区的HFRS监测防治工作。Objective To understand the pattern of epidemic areas of hemorrhagic fever with renal syndrome （HFRS） in Fujian and to provide scientific basis for its prevention and control. Methods Rats were captured in springs and autumns by live snap method, and its density and specie composition were investigated. The virus antigen from rodent lungs was isolated and identified. Results The dominant species in residential areas was Rattus norvegicus in Rattus type areas and the mixed-type area, which density were 4.91% and 5.73% at home respectively. While in the field, it was Apodemus agrarius with the average density of 12.95%, which was obviously higher in autumn and winter than that in spring. R.norvegicus mainly carried with Type II virus, and Ap.agrarius with Type I virus. A44 and R50 virus strain were isolated from them, respectively. Conclusion R.norvegicus was still the main host of HFRS in Fujian. Ap.agrarius was the main host in the field in the diversity epidemic area. It should strengthen the surveillance and the control of HFRS in main epidemic areas.

关 键 词：肾综合征出血热病毒 宿主 啮齿动物 

分 类 号：R373.32[医药卫生—病原生物学] S443[医药卫生—基础医学]