大孔树脂纯化山楂叶提取物的工艺考察  

Study on purification technology of folium crataegi extract by macroporous resin

作　　者：郝彧[1] 刘虹[1] 吴帅[1] 朱晓月[1] 张德芹[1] 

机构地区：[1]天津中医药大学中医药研究院,省部共建方剂学重点实验室,天津300193

出　　处：《天津中医药》2009年第4期335-337,共3页Tianjin Journal of Traditional Chinese Medicine

基　　金：教育部高等学校科技创新工程重大项目培育基金项目(706013)

摘　　要：[目的]考察山楂叶提取物的大孔树脂纯化工艺。[方法]以金丝桃苷为指标,考察了上样量、洗脱溶剂的浓度及用量、树脂重复使用次数、再生后吸附力的恢复等。[结果]选择D101大孔树脂,上样量为树脂体积:生药=1:0.5g(v/w),洗脱溶剂4倍量为70%乙醇。[结论]工艺经济简单实用,可以应用于纯化山楂叶提取物。[Objective] To study the purification technology of Folium Crataegi extract by macroporeus resin. [Method] Taking hyperin as the index constituent, sampling amount and elution solvent were decided, the times for repeated use and recovery capacity after regeneration were studied. [Results] D 101 was chosen to purify, the suitable sampling ratio of resin volume to raw material is 1：0.5. The elution solvent is 4-fold 70% ethanol. [Conclusion] The technology set up was economy, simple and practical, which can be used to purify Folium Crataegi extract.

关 键 词：山楂叶 大孔树脂 金丝桃苷 

分 类 号：R284[医药卫生—中药学]