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机构地区:[1]仲恺农业工程学院医院,广州510225 [2]广东药学院门诊部,广州510226
出 处:《保健医学研究与实践》2009年第3期33-35,共3页Health Medicine Research and Practice
摘 要:目的探讨老年与青年支气管哮喘的临床特点,提高其防治效果。方法收集住院与门诊支气管哮喘380例,其中老年组230例,青年组150例,调查家族遗传史、哮喘临床类型、疗效、预后、并存病等,予以对比分析。结果有阳性家族史者,青年组为53.33%,老年组为30.43%,差异有统计学意义(χ2=19.93,P<0.01);老年组哮喘内源性占60.87%,青年组外源性占66.67%,两组哮喘类型的差异有统计学意义(χ2=27.54,P<0.01);老年组有86.97%的病人合并其他疾病,青年组仅2.67%并存其他疾病,老年组病情严重程度、常反复发作比例、治疗效果与青年组比较,两组差异均有统计学意义(P<0.05或P<0.01)。结论老年支气管哮喘以内源性居多,中、重度多见,并存病多,疗效差,死亡率高,而青年人哮喘以外源性为主,多有遗传倾向,少有并存病,病情以轻中度多见,疗效好,复发率低。Objective To study the clinical features of bronchial asthma of the elderly and the young, to improve the prevention and treatrent. Method To collect 380 cases of bronchial asthma, of which 230 cases were in old age group, 150 cases in young group, to investigate the family history, asthma, clinical types, efficacy, prognosis, disease and other co-exist, and to make comparison and analysis. Results Were with 55.33% in yowth group positive family history, 30.43% for the older group, the difference was statistically significant (2 = 19.93,P〈0.01) ; elderly endogenous asthma 60.87%, accounting for the young group of exogenous 66.67%, two types of asthma have a statistically significant difference (X^2= 27.54, P〈0.01) ; old age group, 86.97% for patients with other diseases, only 2.67 % percent of youth groups exist in other diseases, the severity of the disease in elderly group, often repeated the proportion of attacks, treatment effects worse than the young group, the two groups were statistically significant differences (P〈0.05 or P〈0.01). Conclusion Derived within senile bronchial asthma and more severe common, both diseases, and efficacy of poor, high mortality, but other than asthma derived mainly young people, more than a genetic tendency to co-exist very few cases, the disease to light in degree of common, good efficacy, low relapse rate.
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