房颤转复窦律后无症状患者新发血栓形成及华法林对其影响的研究  

The incidence of the new thrombosis in asymptomatic patients after recovering from atrial fibrillation to sinus rhythm and the influence of warfarin

作　　者：杨光全[1] 

机构地区：[1]山东省菏泽市立医院,274031

出　　处：《中国医学创新》2009年第22期1-3,共3页Medical Innovation of China

摘　　要：目的研究心房颤动(房颤)患者转复窦性心律后无症状者新发血栓的发生率及华法林对其影响。方法回顾性分析242例房颤转复窦律后的无症状患者,分析住院转复房颤期间(第1次)及转复后随访(第2次)的临床资料及经食道心脏超声(TEE)结果,观察新发血栓的情况;比较服用华法林及未服用组新发血栓的发生率。结果 (1)第1次TEE 85例患者均未发现心腔内血栓形成,第2次TEE发现新发血栓18例(21.2%),其中8例有无症状房颤发作;(2)房颤转复窦律后的无症状患者中60.5%(55/85)并发糖尿病;新发血栓的患者中72.2%(13/18)并发糖尿病;(3)华法林组和非华法林组之间的新发血栓的发生率分别为12.8%和31.6%,差异显著(P<0.05)。结论 (1)房颤患者转复窦律后无症状患者新发血栓的发生率较高,其可能主要由无症状房颤所致;(2)房颤患者转复窦律后无症状患者中合并糖尿病的比例较高;(3)华法林可降低房颤患者转复窦律后无症状患者新发血栓的发生率。Objective To observe the incidence of the new thrombosis in asymptomatic patients after recovering atrial fibrillation to sinus rhythm and the influence of warfarin. Methods A retrospective analysis was given to 85 cases of asymptomatic patients after recovering from atrial fibrillation to sinus rhythm, and there clinical datas and information of transesophage- al echocardiography （ TEE ） , then the TEE was checked again with recording the new of thrombosis. To observe the incidence of the group of warfarin and group of non - warfarin. Results （ 1 ） 18 eases of the new thrombosis were found in intracavitary during the second TEE （21.2%）, in whom 8 cases of asymptomatic atrial fibrillation attack; （2）The proportion of patients with diabetes was 60.5 % （55/85） in asymptomatic patients after recovering from atrial fibrillation to sinus rhythm, and 72. 2% （13/18） in patients with the new thrombosis; （3）There was the statistical significance for the incidence of the new thrombosis between group of warfarin and group of non - warfarin. Conclusion （ 1 ） There was a higher rate of the new occurrence of thrombosis in asymptomatic patients after recovering from atrial fibrillation to sinus rhythm . It＇s mainly due to the asymptomatie atrial fibrillation;（2） There was a higher proportion of diabetes in asymptomatic patients after recovering from atrial fibrillation to sinus rhythm ; （ 3 ） Warfarin can reduce the the incidence of the new thrombosis in asymptomatie patients after recovering from atrial fibrillation to sinus rhythm.

关 键 词：心房颤动 无症状 血栓形成 窦性心律 

分 类 号：R541.75[医药卫生—心血管疾病]