男性HIV感染者甲状腺功能与性激素水平的研究  

Research on thyroid function and levels of sexual hormone in males with HIV infection

作　　者：柯亭羽[1] 杜娟[1] 潘毅[1] 洪立珠 袁卫红[3] 徐勉[1] 

机构地区：[1]昆明医学院第二附属医院老年内分泌科,云南昆明650101 [2]云南省艾滋病关爱中心 [3]昆明医学院第二附属医院核医学科

出　　处：《云南医药》2009年第4期414-417,共4页Medicine and Pharmacy of Yunnan

基　　金：云南省教育厅科研基金项目(520298C)

摘　　要：目的研究HIV感染的男性患者是否存在甲状腺功能障碍及性激素水平变化,观察甲状腺激素变化与性激素变化之间的关系。方法采用放射免疫法测定研究对象的甲状腺激素及性激素,分析两者间的相关性。结果1.21.23%的患者出现一种或多种甲状腺激素的改变,12.77%的发生亚临床甲减。2.T,E2,LH,FSH改变差异显著(P<0.05)。3.有甲状腺激素值有变化比甲状腺激素值无变化的患者T下降更明显(P<0.05)。结论1.HIV感染男性患者存在甲状腺激素的紊乱;2.HIV感染男性患者存在性激素的紊乱;3.存在甲状腺激素的紊乱的HIV感染男性患者性激素紊乱更明显。Objective To research the thyroid dysfunction and changes of sexual hormone level in males with HIV infection, and to observe the correlation between changes of thyroid hormone and sexual hormone. Methods To determine thyroid hormone and sexual hormone of patients with As much as 21.23% of the patients had one or more changes HIV infection,and analyze its correlation. Results 1. of thyroid hormone, 12.77% of the patients had the occurrence of subclinical hypothyroidism. 2. There were significant changes of T, E2,LH and FSH （P〈0.05）. Conclusion 1.Thyroid hormone disorders in male patients with HIV infection exist. 2. Sexual hormone disorders in male patients with HIV infection exist. 3. Sexual hormone change is more significant in HIV-infected male patients with thyroid hormone disorders.

关 键 词：获得性免疫缺陷综合征 甲状腺功能 性激素 

分 类 号：R544.1[医药卫生—心血管疾病]