中西医结合治疗2型糖尿病临床回顾性研究  

A Retrospective Study on Type 2 Diabetes Mellitus Treated with Integrated Chinese and Western Medicine

作　　者：刘焱[1,2] 王学美[1] 杨金霞[1] 李娌[1] 杨丽华[1] 李敏芳[1] 富宏[1] 褚松龄[1] 王文利[1] 冼慧[1] 

机构地区：[1]北京大学第一医院中西医结合研究室,北京100034 [2]北京航天中心医院

出　　处：《中国中西医结合杂志》2009年第8期698-702,共5页Chinese Journal of Integrated Traditional and Western Medicine

基　　金：北京市科委重大项目课题(No.H020920010330)

摘　　要：目的比较不同方法治疗2型糖尿病(T2DM)患者的疗效及成本。方法依托住院电子病历信息采集系统收集病例,按治疗方法分为单纯西药治疗、西药治疗合并中药注射剂治疗、西药合并中药汤剂或中成药治疗。采集症状积分、血糖、血脂等数据,分别对3种治疗方法治疗的患者,进行频数统计、分析(计数资料用χ2检验,计量资料用方差分析),比较住院前、住院后及出院1年后在改善症状、提高生活质量、控制血糖、减少胰岛素用量、减少经济负担等情况。结果在改善症状、提高生活质量、控制血糖、减少胰岛素用量、减少经济负担等方面,西药合并中药汤剂或中成药治疗优于单纯西药治疗、西药治疗合并中药注射剂治疗(P<0.05)。结论西药结合中药治疗推荐辨证用药,中药注射剂不建议作为糖尿病治疗的首选方案。Objective To compare the therapeutic efficacy and cost-efficacy of different treatment methods for treatment of type 2 diabetes mellitus （T2DM）. Methods Based on the electronic inpatient clinical information systems, clinical materials of T2DM patients were collected and assigned according to the therapeutic method used, to the groups of Western medicinal （WM） treatment （A）, WM combined Chinese drug injection treatment （B） and the WM combined Chinese decoction or patent drugs treatment （C）. Depending on the data of symptom scores, blood sugar and blood lipids, etc., the efficacy of different treatments were analyzed in terms of improving symptoms, elevating the quality of life （ QOL）, controlling blood sugar, reducing dosage of insulin used and diminishing economic expense, with the enumeration data analyzed by X2 test and the measurement data by ANOVA. Results Treatment C showed a better efficacy than the other two in improving symptoms, elevating QOL, controlling blood sugar, reducing dose of insulin used and lightening the financial burden （P 〈 0.05）. Conclusion Selective use of Chinese drugs depending on syndrome differentiation is recommended during combined application of Chinese and Western medicine; and the Chinese medicine injection is not advised as the first scheme for treatment of T2DM.

关 键 词：糖尿病 中西医结合治疗 成本-疗效 

分 类 号：R587.1[医药卫生—内分泌]