草甘膦化学合成工艺及其中间体的生物法合成技术展望  

Perspective of Chemosynthesis Methods of Glyphosate and Biosynthesis of Glyphosate Intermediate

作　　者：林志坚[1] 郑仁朝[1] 楼亿圆[1] 郑裕国[1] 沈寅初[1] 

机构地区：[1]浙江工业大学生物工程研究所,杭州310014

出　　处：《农药》2009年第8期547-551,共5页Agrochemicals

基　　金：国家重点基础研究发展规划项目(2007CB714306);浙江省自然科学基金项目(Y4080334)

摘　　要：草甘膦是世界上应用广、产量大的除草剂。介绍了草甘膦的特性和市场,综述了国内外草甘膦的生产工艺,展望了今后我国草甘膦生产的发展方向和前景。创新性地提出了用微生物腈水解酶催化法制备草甘膦中间体亚氨基二乙酸的可行性。Glyphosate herbicide is the most commonly used and largest-selling agrochemical in the world. The features, market and production processes of glyphosate were reviewed. Then the development trends and prospects of its production in China were discussed. Finally, the feasibility of biosynthesis of iminodiacetic acid, an important intermediate of glyphosate using nitrilase, was innovatively put forward.

关 键 词：草甘膦 亚氨基二乙酸法 甘氨酸-亚磷酸二烷基酯法 亚氨基二乙腈 腈水解酶 

分 类 号：TQ457.2[化学工程—农药化工]