小儿利咽康颗粒剂对小鼠体内外抑菌作用的实验观察  

Experimental observation on internal and external inhibition of bacteria with Liyankang granule for children

作　　者：宋光熠[1] 王实[1] 张广新[1] 刘永林[1] 李开明[1] 

机构地区：[1]辽宁中医药大学职业技术学院医学基础部,沈阳110101

出　　处：《中国中西医结合儿科学》2009年第4期316-317,共2页Chinese Pediatrics of Integrated Traditional and Western Medicine

摘　　要：目的观察小儿利咽康颗粒剂的体内外抑菌作用。方法采用90%小鼠死亡量甲型链球菌液腹腔注射感染小鼠,观察小儿利咽康颗粒剂的体内抑菌作用;通过抑菌圈直径测定,观察小儿利咽康颗粒剂的体外抑菌作用。结果小儿利咽康颗粒剂可明显提高甲型链球菌感染小鼠的存活时间,对甲型链球菌、乙型链球菌、金黄色葡萄球菌、肺炎球菌、流感杆菌、大肠杆菌、福氏痢疾杆菌有不同程度的抑制作用。结论小儿利咽康颗粒剂具有抑菌作用。Objective To observe the internal and external inhibition of bacteria with Liyankang granule for children. Methods The 90% lethal dose（LD90） of alpha streptococcus liquid was givn by abdominal injection to infect small rats in order to observe internal inhibition of bacteria with Liyankang granule for children. Through defermination of diameter of inhibiting bacteria circle, we observed the external inhibition of bacteria with Liyankang granule for children. Results Liyankang granule for children could obviously expand survival time of small rats infected by alpha streptococcus,having certain inhibition on beta streptococcus, Staphylococcus aureus, pneumococcus, Bacillus influenzae, colon bacillus and Sh. flexneri. Conclusion Liyankang granule for children has has the effect of inhibiting inhibition of bacteria.

关 键 词：利咽康颗粒剂/治疗应用 炎症 中草药/治疗应用 小鼠 动物 实验 

分 类 号：Q95-3[生物学—动物学] R725[医药卫生—儿科]