广西珠蛋白生成障碍性贫血干预模式探讨  

The research on intervention model of thalassemia syndrome in Guangxi autonomous region

作　　者：吕福通[1] 谢丹尼[1] 陈一君[1] 陈美佳[1] 周艳洁[1] 

机构地区：[1]广西壮族自治区人口和计划生育研究中心,广西南宁530021

出　　处：《中国计划生育和妇产科》2009年第4期14-17,共4页Chinese Journal of Family Planning & Gynecotokology

摘　　要：目的探讨珠蛋白生成障碍性贫血的干预模式。方法建立珠蛋白生成障碍性贫血干预示范点，对新婚夫妇和其他已婚待孕夫妇进行珠蛋白生成障碍性贫血的检测；建立珠蛋白生成障碍性贫血夫妇的数据库，对珠蛋白生成障碍性贫血高危夫妇进行跟踪随访，督促落实产前诊断措施。结果在3个示范点，共为85857人开展珠蛋白生成障碍性贫血检测，检出珠蛋白生成障碍性贫血19886人次，发现高危夫妇1507对，跟踪产前诊断307例，避免了91例重症珠蛋白生成障碍性贫血患儿的出生。结论在广西实施珠蛋白生成障碍性贫血的干预工作，能有效减少珠蛋白生成障碍性贫血出生缺陷患儿的出生，是提高广西出生人口素质的重要措施。Objective To investigate the intervention mode of thalassemia syndrome. Methods The estab- lishment of demonstration sites of thalassemia Syndrome intervention on the newly married couples and other married couples to be pregnant for the detection of thalassemia syndrome; To establish a database of thalassemia syndrome couples, and follow-up the couples with high - risk of thalassemia syndrome so as to supervise the implementation of prenatal diagnosis. Results In the three demonstration sites, a total of 85,857 people were carried out the examina- tion of thalassomia syndrome. As the result, 19,886 patients of thalassemia syndrome were detected, 1507 pairs of high - risk couples were detected and 307 pregnant women were carried out the prenatal diagnosis to avoid 91 infants with severe thalassemia syndrome to be born. Conclusion The implementation of interventions on thalassemia syndrome was effective in reducing the amount of children with birth - defect of thalassemia syndrome and It was an im- portant measure to improve the quality of the population in Guangxi autonomous region.

关 键 词：珠蛋白生成障碍性贫血 干预模式 

分 类 号：R556.6[医药卫生—血液循环系统疾病]