胎儿窘迫对新生儿神经行为的影响及其预后的初步研究  

Influence of Fetal Distress on Neonatal Behavior Neurological Assessment and Its Prognosis

作　　者：王沂峰[1,2] 王广润[1,2] 曲显旭 孙若鹏 程建萍[1,2] 

机构地区：[1]山东医科大学附属医院妇产科 [2]济南中心医院儿科

出　　处：《中华妇产科杂志》1998年第8期475-478,共4页Chinese Journal of Obstetrics and Gynecology

摘　　要：目的测定宫内窘迫的新生儿神经行为及其幼儿期的智能发育，以探讨宫内窘迫与新生儿神经行为表现和预后的关系。方法新生儿期用新生儿神经行为２０项指标测定，２岁时用改良的韦克斯勒量表测定其智力发育。结果宫内窘迫新生儿６０例（窘迫组）与正常新生儿６０例（对照组）比较，测定总分之间差异有极显著性（Ｐ＜０．０１），窘迫组中４１例无窒息者与对照组比较，差异有显著性（Ｐ＜０．０５），窘迫组中１９例有窒息者与对照组差异更为显著（Ｐ＜０．００１），急性窘迫３８例与慢性窘迫２２例之间也有显著差异（Ｐ＜０．０１）。幼儿２岁时智力测试显示，３８例急性窘迫儿与对照组无统计学差异，而２２例慢性窘迫儿与对照组相比差异有显著性（Ｐ＜０．０１）。结论胎儿窘迫可影响新生儿的神经行为能力，对幼儿期的智力发育也有一定影响。Objective To study the short and long term prognosis of fetal distress. Methods 60 newborns with fetal distress (study group) and 60 normal newborns (control group) were assessed by neonatal behavior neurological assessment (20 items) in neonatal period and by reformed wechsler intelligence scale childrenrevised at 2 years of age. Results The total scoring of study group was significantly different from that of control group (P<0.01). In the study group, there were 41 cases without neonatal asphyxia whose scoring was significantly different from that in the normal group (P<0.05), whereas the scoring of other 19 cases with neonatal asphyxia was significantly lower than that of the control group (P<0.001). We also found that the scoring of 38 acute fetal distress cases was significantly different from that of 22 chronic cases (P<0.01). In two years followup study, the scoring of children's intelligence test in acute distress cases was not different from that of controls, but the scoring of intelligence test in chronic distress cases was markedly different from that of controls (P<0.01). Conclusion Fetal distress could affect neonatal behavior and their intellectual development.

关 键 词：胎儿窘迫症 新生儿 智力测验 神经行为 预后 

分 类 号：R714.43[医药卫生—妇产科学] R748.01[医药卫生—临床医学]