^(99m)Tc-DTPA肾动态显像在小儿肾盂积水中的应用  

The application of ^(99m)TcDTPA renal dynamic imaging in children with hydronephrosis

作　　者：吴靖川[1] 杨淑蓉[1] 曹少平[1] 刘国华[1] 陈方[1] 傅宏亮[1] 邵虹[1] 吴真[1] 吴继琮[1] 

机构地区：[1]上海第二医科大学附属新华医院核医学科

出　　处：《中华核医学杂志》1998年第3期170-172,共3页Chinese Journal of Nuclear Medicine

摘　　要：目的探讨９９ｍＴｃＤＴＰＡ肾动态显像诊断小儿肾盂积水的临床价值。方法常规９９ｍＴｃＤＴＰＡ肾动态显像方法，１５分钟后静脉注射速尿，共检查肾盂积水患儿４５例，其中７例作手术前后比较。定量分析指标包括：肾血流灌注率（ＢＰＲ），高峰摄取率（ＰＵＲ），半排泄时间（Ｔ１／２）。结果①ＢＰＲ随积水程度加重而明显下降，重度积水为１６８％±６８％，中度积水为３５１％±６９％，轻度积水为４０６％±９２％。ＰＵＲ在重度积水时为２１６％±１２９％。②７例患儿中６例术后ＢＰＲ明显升高。术前、术后Ｔ１／２分别为４１３±２０４和２２９±１１９分钟。术后Ｔ１／２明显改善。结论①ＢＰＲ可正确反映肾盂积水和肾功能受损程度，两者呈正相关；Purpose To evaluate the clinical value of ^(99m)TcDTPA renal dynamic imaging for diagnosis of child hydronephrosis Methods 45 children with hydronephrosis were examined by ^(99m)TcDTPA renal dynamic imaging combined with intravenous injection of furosemide, seven of them had surgical treatment and underwent the dynamic imaging pre and postoperation Furosemide was given 15 minutes after injection of imaging agent Quantitatively analysed renal blood perfusion rate (BPR), peak uptake rate (PUR) and half washout time after furosimide injection (T_1/2) Results The more the hydronephrosis deteriorated, the lower the BPR was; severe cases: 16.8%±6.8%, moderate cases: 35.1%±6.9%, mild cases: 40.6%±9.2% T_1/2 of normal kidney was 14.9±6.3min T_1/2 of hydronephrosis kidney was 41.3±20.4min before operation BPR significantly increased, and T_1/2 speeded up to 22.9±11.9 after effective operation Conclusions ①BPR can be used as an index of good correlation for the existance of hydronephrosis and the damage intensity of renal function ② ^(99m)TcDTPA renal dynamic imaging is helpful for the judgement of urinary obstruction

关 键 词：肾积水 放射性核素显像 DTPA 儿童 

分 类 号：R726.923[医药卫生—儿科] R817.47[医药卫生—临床医学]