短柱肖菝葜中的一个新化合物  

Isolation of A new compound of Heterosmilax yunnanensis Gagnep

作　　者：秦文杰[1,2] 高寒[2] 王钢力[3] 林瑞超[3] 

机构地区：[1]中药复方新药开发国家工程研究中心,北京100075 [2]河南省中医药研究院,郑州450004 [3]中国药品生物制品检定所,北京100050

出　　处：《中国药学杂志》2009年第14期1056-1059,共4页Chinese Pharmaceutical Journal

基　　金：北京市科技计划项目(D0206001043491)

摘　　要：目的对短柱肖菝葜的化学成分进行研究。方法应用多种色谱技术进行分离纯化,通过理化方法和波谱数据进行结构鉴定。结果分离并鉴定了3个化合物,分别为2-O-α-L-鼠李吡喃糖基-5-C-β-D-葡萄吡喃糖基-4,6-二羟基-苯基-对羟基苯酮(Ⅰ);大豆素(Ⅱ)和β-谷甾醇酯-3β-吡喃葡萄糖苷-6′-O-棕榈酸酯(Ⅲ)。结论Ⅰ为新化合物,简易命名为肖菝葜苷B;所有化合物均系首次从该属植物中分离得到。OBJECTIVE To study the chemical constituents of Heterosmilax yunnanensis Gagnep. METHODS The compounds were isolated and purified by chromatography. The structures were elucidated by physico-chemical properties and spectral analysis. RESULTS Three compounds were obtained and identified as 2-O-α-L-rhamnopyranosyl- 5-C-β-D-glucopyranosyl-4,6-dihydroxyl-phenyl-p-hydroxy benzophenone（ Ⅰ ）, liquiritigenin（Ⅱ） and β-sitosteryl-3β-glucopyran oside-6 ′ -O-palmitate（Ⅲ）. CONCLUSION Compound I is a novel compound and simply named as Heterosmioside B. Thgy were isolated from the Heterosmilax for the first time.

关 键 词：短柱肖菝葜 化学成分 高速逆流色谱法 肖菝葜苷B 

分 类 号：R284.1[医药卫生—中药学]