医院感染金黄色葡萄球菌的分布与耐药性调查  

Clinical Distribution and Drug-resistance in Nosocomial Infections with Staphylococcus aureus

作　　者：邹启富[1] 闵文静 范文[2] 

机构地区：[1]荆州市第一人民医院长江大学临床医学院核医学科,湖北荆州434000 [2]荆州市第一人民医院长江大学临床医学院检验科,湖北荆州434000

出　　处：《中华医院感染学杂志》2009年第16期2179-2180,共2页Chinese Journal of Nosocomiology

摘　　要：目的调查医院临床分离的金黄色葡萄球菌(SAU)耐药现状,为临床医师合理使用抗菌药物提供科学依据。方法对311株SAU的标本来源和临床科室分布进行回顾性调查分析,SAU均由VITEK 32细菌分析系统进行鉴定;药敏试验采用K-B法进行。结果医院耐甲氧西林金黄色葡萄球菌(MRSA)分离率为48.9%;SAU除对糖肽类抗菌药物100.0%敏感以外,对其他多种抗菌药物均产生了不同程度的耐药性,且MRSA对抗菌药物的耐药率均高于甲氧西林敏感金黄色葡萄球菌(MSSA)。结论加强细菌耐药性的监测与控制,是预防医院感染的有效措施。OBJECTIVE To investigate the drug-resistance status of clinically isolated Staphylococcus aureus （SAU） and provide scientific evidence for clinically reasonable use of antibiotics. METHODS Retrospective review was adopted to analyze the specimen source and the clinical distribution of 311 SAU strains. BioMerieux VITEK 32 was used to identify SAU. Antibiotic susceptibility testing was performed by K-B method. RESULTS Isolating rate of meticillin-resistant S. aureus （MRSA） was 48. 9%. SAU were resistant to the diverse antibiotics in different degree except for 100% sensitivity to glycopeptide antibiotics. The drug-resistance to antibiotcs in MRSA were all higher than those in meticillin-sensitive S. aureus （MSSA）. CONCLUSIONS Monitoring and controlling of antibiotics resistance are effective measures of prevention from nosocomial infections.

关 键 词：金黄色葡萄球菌 医院感染 临床分布 耐药性 

分 类 号：R378.11[医药卫生—病原生物学]