血管紧张素Ⅱ受体拮抗剂对阵发性房颤患者P波离散度的影响  

Effects of Angiotensin Ⅱ Receptor Blocker on P Wave Deviation Degree in Patients with Paroxysmal Atrial Fibrillation

作　　者：赵国忠[1] 陈晨[1] 冯小兰[1] 林蔚[1] 瞿龙[1] 

机构地区：[1]四川省科学城医院心内科,四川绵阳621900

出　　处：《华西医学》2009年第6期1445-1446,共2页West China Medical Journal

摘　　要：目的:探讨血管紧张素Ⅱ受体拮抗剂(ARB)对PAF患者P波离散度的影响。方法:观察48例阵发性AF患者的最宽P波和P波离散度,并与ARB干预治疗3个月后进行对比分析。结果:ARB治疗3个月后最宽P波、P波离散度及P波离散度≥40 ms的例数与治疗前比较差异有统计学意义(P<0.05或<0.01)。结论:ARB能减轻PAF患者心房结构重构及电重构,减少AF的发生。Objective： To investigate the effect of angiotensin Ⅱ receptor blocker on P wave deviation degree in patients with paroxysmal atrial fibrillation.Methods： Forty-eight patients with paroxysmal atrial fibrillation had taken angiotensin Ⅱ receptor blocker for three months.The widest P wave and P wave deviation degree was measured before and after treatment.Results： After treatment the widest P wave,P wave deviation degree and the cases of P wave deviation degree ≥40 ms were significantly reduced compared with those before treatment（P〈 0.05 or P〈 0.01）.Conclusion： Angiotensin Ⅱ receptor blocker lessens atrial structure and electric remodeling,and decreases incidence of atrial fibrillation.

关 键 词：血管紧张素Ⅱ受体拮抗剂 阵发性AF P波离散度 

分 类 号：R541.7[医药卫生—心血管疾病]