ICU标本细菌培养结果及耐药性分析  

Analysis of bacteria and their drug resistance in intensive care unit

作　　者：王玉萍[1] 李小宁[1] 王明华[1] 刘春生[1] 

机构地区：[1]皖南医学院附属弋矶山医院检验科

出　　处：《中国临床药理学与治疗学》2009年第6期691-694,共4页Chinese Journal of Clinical Pharmacology and Therapeutics

摘　　要：目的:了解ICU病人感染细菌的分布及耐药情况。方法:留取ICU 228份标本进行培养,阳性标本进行细菌鉴定及药敏分析。结果:228份标本中检出细菌186份,占81.6%,其中G+球菌42份,占18.4%,G-杆菌144份,占63.2%;阳性球菌中以金黄色葡萄球菌最常见,阴性杆菌中依次以不动杆菌、铜绿假单胞菌、肺炎克雷伯菌多见。186例药敏结果中G+球菌除万古霉素全敏感外,其余药敏结果耐药率均达80%以上;G-杆菌药物敏感率头孢哌酮/舒巴坦>哌拉西林/他唑巴坦>美罗培南,铜绿假单胞菌对头孢他啶的耐药率为31%,对其余药物耐药率均达60%以上。结论:ICU病人细菌感染率高,感染细菌种类多,细菌耐药率高,应根据药敏结果合理选用抗生素。AIM： To study the distribution of infectived bactarial In ICU and analyze their drug resistant rates. METHODS：228 specimens were cultivated, the identification of bacteria and drug susceptibility were tested in the positive specimens. RESULTS： 186 specimens including bacteria were detected from 228 （accounted for 81.6%）, which 42 specimens including gram positive coccus （ accounted for 18.4 % ）, and 144 specimens including gram negative bacilli（ accounted for 63.2 % ）, the staphylococcus aereus was primary in gram positive coccus, the first three bacilli were acinetobacter, pseudomonas aeruginosa, klebsiella pneumonice in gram negative bacilli, the resistant rates of the gram positive bacterium to other drugs were more than 80% except perfectly susceptibility to vancomycin, the decreasing susceptibility order among gram negative bacilli was cefoperazone/sulbactam, piperacillin/tazobactam , Meropenem. The resistant rate of pseudomonas aeruginosa to ceftazidime was 31%, the resistant rates to other drugs were more than 60%. CONCLUSION： There is higher infected rate, more kinds of infected bactiria and more serious resistant rates to ICU patients, it is necessary to choose antibiotic reasonably according to the results of drug susceptibil.

关 键 词：ICU 耐药性 细菌 

分 类 号：R117[医药卫生—公共卫生与预防医学]