P物质在正常与致聋白腰文鸟前脑X区表达水平的差异研究  

DIFFERENT SUBSTANCE P EXPRESSION IN AREA X IN NORMAL AND DEAFENED BENGALESE FINCH

作　　者：张颖[1] 尉红季[1] 孙颖郁[1] 左明雪[1] 

机构地区：[1]北京师范大学生命科学学院,北京100875

出　　处：《北京师范大学学报（自然科学版）》2009年第4期385-388,共4页Journal of Beijing Normal University(Natural Science)

基　　金：国家自然科学基金资助项目（30670685;30870307）

摘　　要：通过免疫组织化学方法对正常和致聋不同时程的成年雄性白腰文鸟X区P物质的表达进行了定量分析,结果发现：致聋后鸟的X区P物质表达量显著减少.X区是鸣禽鸣唱学习的重要核团,P物质也是一种重要的神经调质,提示X区P物质可能参与了鸣禽鸣唱可塑性的调节或鸣唱模式的维持.Substance P expression in area X in normal and deafened Bengalese finchs was analyzed by immunohistochemistry. It was found that substance P expression decreased significantly after deafening. Area X is an important nucleus of song learning, and substance P is an important neuro-modulator. These data suggest that substance P expression in area X is related to plasticity modulation or song model maintenance.

关 键 词：X区 P物质 致聋 消减平均灰度 

分 类 号：Q959.7[生物学—动物学] Q42