糖克宁颗粒质量标准研究  

Study on quality standard for Tangkening Granule

作　　者：袁强[1] 楼云娜 

机构地区：[1]浙江中医药大学附属二院,杭州310005 [2]浙江普洛康裕制药有限公司,东阳322118

出　　处：《中华中医药杂志》2009年第8期1087-1089,共3页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：浙江省中药现代化专项资金项目(No.浙财建字[2006]164号)

摘　　要：目的:研究糖克宁颗粒的质量标准。方法:采用薄层色谱法对制剂中的栀子、绞股蓝、山药等进行鉴别,采用HPLC法对糖克宁颗粒中的栀子苷进行含量测定。结果:薄层色谱斑点清晰,可鉴别出栀子、绞股蓝、山药,阴性对照无干扰。平均加样回收率为99.9%,RSD为2.9%(n=6)。结论:该方法专属性强、重现性好,可用于糖克宁颗粒的质量控制。Objective： To establish the quality standard for Tangkening Granule. Methods： Gardenia, Gold Theragran and batatatis in Tangkening Granule were identified by TLC, the content of geniposide was determined by HPLC. Result： The spots in TLC was clear, the negative control had no interference, the average recovery was 99.9%, RSD was 2.9%（n=6）. Conclusion ： The method was accurate, reproducible and specific. It can be used for quality control of Tangkening Granule.

关 键 词：糖克宁颗粒 栀子苷 薄层色谱法 高效液相色谱法 

分 类 号：R286.0[医药卫生—中药学] R259.871[医药卫生—中医学]