高血压患者动态血压监测尿微量白蛋白的意义  

About of the comparison on ambulatory blood pressure of essential hypertension with microalbuminuria

作　　者：施红领[1] 马志刚[1] 马艳萍 

机构地区：[1]银川市第一人民医院,宁夏银川750001 [2]宁夏平罗县中医医院,宁夏平罗753400

出　　处：《宁夏医学杂志》2009年第8期705-706,共2页Ningxia Medical Journal

摘　　要：目的探讨高血压(EH)动态血压(ABPM)监测尿微量白蛋白(ALB)的意义。方法用放免法测定242例EH患者的尿ALB,根据结果将患者分为ALB组和非ALB组。所有患者行24hABPM监测,并分析其特点。结果ALB组昼夜节律消失,24h平均收缩压(24hSBP)、平均脉压(24hPP);日间平均收缩压(dSBP)、平均脉压(dPP);夜间平均收缩压(nSBP)、平均脉压(nPP)明显高于非ALB组,差异有统计学意义(P<0.05)。结论ALB组患者正常的杓型ABPM节律消失较明显,收缩压尤其是夜间收缩压对反映早期肾损伤具有更重要的作用。Objective To study the ambulatoy blood pressure feature of essential hypertension with Microalbuminuria. Methods Microalbuminuria concentrations were detected by radioimmunoassay. Based on abve results, the patients were divided into two groups：the Microalbuminuria group an the None Microalbuminuria group, and then 24hABPM were measured in the hypertensive patients. Results The rate Circaian rhythm disappeatance of blood pressure,24hSBP, 24hPP, dSBP, dPP, nSBP, nPP,in the group of essential hypertension with Microalbuminuria were significantly high than that in the group of essential hypertension withour Microalbuminuria, there have significantly difference （P 〈 0. 05 ）. Conclusion Essential hypertension with Microalbuminuria patients have lost the normal dipper rhythm of ambularory blood pressure obviously, especially rising in stress of SBP, NSBP, systolic blood pressure may play an important role in the earlier renal damage ABPM was superior in predicting damage of tatget organ of kidney.

关 键 词：高血压 微量蛋白尿 24H动态血压监测 动态血压节律 

分 类 号：R544.1[医药卫生—心血管疾病]