GC-MS法检测广藿香挥发油的化学成分  

Detection of Essential Oils from Pogostemon Cablin by GC-MS

作　　者：刘志华[1] 周德英[2] 

机构地区：[1]河北工业大学化工学院,天津300130 [2]天津中新药业隆顺榕制药厂,天津300457

出　　处：《中国农学通报》2009年第16期95-98,共4页Chinese Agricultural Science Bulletin

基　　金：天津市重点科技攻关项目"建设高新技术示范工程"(023182211)

摘　　要：广藿香是藿香正气水等中成药的主要药味,广藿香的主要有效成分是广藿香挥发油,为保证药品的疗效和质量,需建立准确评估广藿香原料品质的检测方法。采用GC-MS法对广藿香挥发油成分进行了定性和量化分析,得到了九个特征峰。实验结果表明这九个特征峰的重复性、稳定性、重现性良好,适合作为广藿香挥发油的指纹图谱的基础数据。通过对市售三个不同批次的原料分别进行分析,上述九个特征峰为三批材料共有的特征峰,因此这9个共有峰可作为广藿香挥发油的指纹图谱。尽管不同批次样品的挥发油各组分的含量有显著差异。但选择九个特征峰及广藿香酮与广藿香醇的峰面积比值可以作为控制质量的指标参数。建议在使用广藿香原料时应根据产品的不同特点建立广藿香油的指纹图谱质量标准。The main component of Pogostemon cablin is essential oils. It is necessary to establish the quantitative determination on Pogostemon cablin content. The essential oil was analyzed quantitatively and qualitatively on GC-MS instrument; for controlling the quality, GC fingerprint of Pogostemon cablin was set up. Nine compounds including patchouli alcohol and pogostone were identified among 9 main peaks in three samples sold in the market. The fingerprint can help distinguish the quality and assess the differences of Pogostemon cablin by ratio of patchouli alcohol and pogostone from various areas in China.It is necessary to establish quantitative standard by the fingerprint of essential oils extracted from Pogostemort cablin.

关 键 词：广藿香 挥发油 GC指纹图谱 

分 类 号：R248.2[医药卫生—中医临床基础]