泥敷与堆敷灭螺土壤中氯硝柳胺含量及其灭螺效果  

Study on concentration of niclosamide in soil through soil pasting and heaping mixed with niclosamide and the effect on snail control

作　　者：何明祯[1] 周艺彪[1] 周颖[2] 王海银[1] 依火伍力[3] 刘刚明[3] 姜庆五[1] 

机构地区：[1]复旦大学公共卫生学院流行病学教研室、教育部公共卫生安全重点实验室,上海200032 [2]复旦大学公共卫生学院卫生化学教研室 [3]四川省普格县疾病预防控制中心

出　　处：《中国血吸虫病防治杂志》2009年第4期318-320,共3页Chinese Journal of Schistosomiasis Control

基　　金：国家自然科学基金重大项目(30590374);卫生部疾病预防控制局-上海市重点学科建设项目(B118)

摘　　要：目的观察泥敷、堆敷灭螺中氯硝柳胺在土壤中的含量和分布、随时间的变化情况及其与灭螺效果的关系。方法土壤样品分别采自四川省普格县的4个地区,经超声萃取、离心、浓缩后用高效液相色谱测定其含量;灭螺试验分别计算3d和7d钉螺死亡率。结果各组土壤中的氯硝柳胺含量分布很不均匀,采用堆敷灭螺的特兹乡甲木村先锋组、长寿村新建组表层土与深层土氯硝柳胺含量差异无统计学意义(P>0.05);采用泥敷灭螺的荞窝镇安木足村五组与特兹乡长寿村米石组因间隔时间不同,土壤中氯硝柳胺含量差异有统计学意义(P=0);堆敷灭螺法在灭螺13个月后,土壤中仍残留一些氯硝柳胺,并且还有一定的灭螺效果,钉螺死亡率最高达21.26%;钉螺3、7d死亡率与土壤中氯硝柳胺含量的Spearman相关系数分别为0.354、0.306(P均<0.05)。结论堆敷灭螺法因结合了环境改造,灭螺效果优于泥敷法;2种灭螺方法的氯硝柳胺在土壤中的分布不均匀,其含量随着时间的推移逐渐降低,灭螺效果与氯硝柳胺含量有一定的正相关关系。This study aimed to observe the concentration,distribution and decreasing trend of niclosamide in soil by soil pasting and soil heaping mixed with niclosamide and the effect on snail control. The soil samples from four areas in Puge County,Sichuan Province were collected. We found the distribution of niclosamide in soil through soil pasting and soil heaping was very disperse. The concentration of niclosamide in soil was gradually decreasing along with the time. There was a positive relationship between the concentration of niclosamide and the effect on snail control by the two methods. There was a better effect of snail control through soil heaping because of its conjunction with the environment modification.

关 键 词：氯硝柳胺 钉螺 泥敷 堆敷 灭螺 

分 类 号：R383.24[医药卫生—医学寄生虫学]