糖化血红蛋白与冠状动脉病变程度关系的探讨  

Relationship between HbA1c and severity of coronary artery disease in patients underwent coronary angiography

作　　者：申鹰[1] 

机构地区：[1]北京大学航天临床医学院心内科,100049

出　　处：《中国现代医药杂志》2009年第8期23-25,共3页Modern Medicine Journal of China

摘　　要：目的探讨冠心病患者糖化血红蛋白水平与冠状动脉病变程度之间的关系。方法冠状动脉造影住院患者209例,经造影确诊冠心病164例(占78.5%),排除冠心病患者45例(占21.5%)。冠状动脉病变程度以冠状动脉病变的支数表示,分为正常对照组、冠状动脉单支血管病变组、冠状动脉多支血管病变组。所有研究对象检测糖化血红蛋白(HbA1c)、血脂。结果冠状动脉多支血管病变组HbA1c水平(6.65±1.44)%,冠状动脉单支病变组(6.18±1.16)%,冠脉造影正常组HbA1c水平(6.06±1.05)%。冠脉多支血管病变组HbA1c水平较单支病变组及正常对照组高,差异有统计学意义(P<0.05),冠脉单支病变组HbA1c与冠脉造影正常组比较无显著差异。结论血清HbA1c水平对判断冠状动脉病变程度有一定的价值。Objective To investigate the relationship between HbA1c and severity of coronary artery disease. Methods A total of 209 patients were performed coronary angiography. CAD was diagnosed by angiography.The exent and severity of the coronary aetery disease were indicated by the number of diseased vessels. The patients were divided into control group, singlevessel lesion group, muhi-vessle lesion group according to coronary angiography results.All patients were measured HbA1c, serum lipid. Results Level of serum HbA1c in muhi-vessle lesion group was significantly higher than coronary single-vessle lesion group and control groupe. Conclusion HbA1c play a certain role to determine the exent and severity of coronary artery lesion.

关 键 词：冠状动脉疾病 糖化血红蛋白 冠脉血管造影术 

分 类 号：R541.4[医药卫生—心血管疾病] R587.1[医药卫生—内科学]