定量组织多普勒径向应变显像评价心力衰竭患者再同步化治疗效果  

Assessment of Cardiac Resynchronization Therapy for Patients with Heart Failure by Using Quantification Tissue Doppler Radial Strain Imaging

作　　者：武彤[1] 刘望彭[1] 

机构地区：[1]山西医科大学第一临床医院超声科,山西太原030001

出　　处：《中国现代医生》2009年第24期1-2,18,F0003,共4页China Modern Doctor

摘　　要：目的应用径向应变显像评价心力衰竭病人同步化治疗效果。方法心衰双室起搏患者6例,心衰右室起搏患者6例,正常对照组13例。平静状态下获取左室短轴乳头肌水平TDI图像,测定前壁、间隔、下壁、侧壁4个节段收缩期径向应变达峰时间及失同步化时间。结果①HF-RV组、HF-BV组与正常组QRS间期比较,差异有统计学意义(P<0.05),HF-RV组QRS间期高于HF-BV组(P<0.05)。②正常组与HF-BV组内4个节段T-peak,差异无统计学意义(P>0.05),HF-RV间隔的T-peak明显低于其它节段(P<0.05),而且HF-RV失同步化时间明显高于其它两组(P<0.05)。结论径向应变达峰时间能够评价左心室各节段收缩同步性,使用双室起搏更优良地改善了心肌机械同步性。Objective To assess cardiac resynchronization therapy for patients with heart failure by using Quantitative tissue Doppler radial strain imaging. Methods Six heart failure patients with biventricular pacemaker （HF-BV） and six heart failure patients with right ventricular pacemaker （HF-RV） and thirteen normal patients were included. The standard short-axis velocity views of 2-D tissue Doppler imaging （TDI） at the levels of papillary muscle including three cardiac cycles were acquired. By using quantification tissue Doppler imaging （TDI-Q） workstation, the strain-time curves were obtained about anterior wall（AW）, interseptal wall（IS）, posterior wall （PW） and lateral wall （LW） and the time-to-peak radial strain （T-peak） and dyssynchrony time of all the 4 segments were calculated. Results There was a statistical difference in the QRS intervals between HF-RV, HF-BV and normalpatieuts（P〈0.05）. There was no statistical difference in the T-peak of all the 4 segments in HF-RV compared with nonnalpatients（P〉0.05）. The T-peak of interseptal wall in HF-RV was significantly lower than that of other segments （P〈 0.05）. The dyssyuchrony time of HF-RV was significantly greater than that of the other groups （P 〈 0.05）. Conclusion The time-to-peak radial strain is useful to quantify synchrony of the left ventricle. Biventricular pacing is benifical to improve cardiac mechanical synchrony of the left ventricle.

关 键 词：多普勒 应变 起搏 

分 类 号：R541.6[医药卫生—心血管疾病]