Mating behavior induces changes of expression of Fos protein,plasma testosterone and androgen receptors in the accessory olfactory bulb (AOB) of the male mandarin vole Microtus mandarinus  

作　　者：Fengqin HE Fadao TAI 

机构地区：[1]College of Life Sciences, Shaanxi Normal University, Xi＇an 710062, China [2]Department of Life Sciences, Xi＇an University of Arts and Science, Xi＇an 710065, China

出　　处：《Current Zoology》2009年第4期288-295,共8页动物学报（英文版）

基　　金：funded by theNatural Science Foundation of China(30670273);Natural Science Foundation of ShaanXi(2008C269);Science and Technology Plan Project of Xi'an Burea of Science and Technology(YF07194);Special Science Research Fund for Xi'an University of Arts and Science(KY200520)

摘　　要：In order to investigate the neuroendocrine mechanism of the mating behavior in the adult male mandarin voles Microtus mandarinus,the radioimmunoassay(RIA)and immunohistochemistry methods were used to investigate the differences in plasma testosterone(T)concentrations and distribution of T immunoreactive neurons(T-IRs),androgen receptor immunoreactive neurons(AR-IRs)and Fos protein immunoreactive neurons(Fos-IRs)in the accessory olfactory bulb(AOB)and the main olfactory bulb(MOB)following exposure to clean hard-wood shavings(control group),soiled bedding(exposure group)or contact with an estrous female(mating group).Results showed that plasma T concentration was significantly higher in the mating group than that in the exposure group,and both the mating group and the exposure group displayed significantly higher plasma T concentration than the control group.T-IRs,AR-IRs and Fos-IRs were investigated with the immunohistochemistry method in granule cell(GC)and mitral cell(MC)of the MOB and the AOB in the three groups.There were significantly more T-IRs,AR-IRs and Fos-IRs in MC and GC of the AOB in the mating group than that in the exposure group or the control group.T-IRs,AR-IRs and Fos-IRs did not show significant differences between the exposure group and the control group.Furthermore,obvious differences in MC and GC of the MOB were not found among the three groups.The results confirm that both changes of T and AR in the AOB might be underlying mating behavior in the adult male mandarin voles.

关 键 词：Mandarin voles Microtus mandarinus Main olfactory bulb （MOB） Accessory olfactory bulb （AOB） Testosterone（T） Androgen receptor （AR） Fos protein Mating behavior 

分 类 号：Q95[生物学—动物学]