氦氖激光诱导离体小鼠胸腺细胞凋亡的实验研究  

Research of Apoptotic Mice Thymocytes in Vitro Generated by He-Ne Laser Irradiation

作　　者：刘炳荣[1] 史桂英[1] 徐清[1] 

机构地区：[1]上海第二医科大学生物物理教研室,上海200025

出　　处：《中国激光》1998年第8期759-762,共4页Chinese Journal of Lasers

基　　金：国家自然科学基金会信息科学部支助项目

摘　　要：实验发现随着低功率氦氖激光照射时间的延长 (激光剂量的增加 ) ,胸腺细胞凋亡的相对数相应增大 ,表现在其 DNA直方图上可见亚二倍体峰升高。An instant elevation in intracellular Ca 2+ concentration ([Ca 2+] i) appears significant after the irradiation of cells with a He-Ne laser. Studies using various cell types have demonstrated changes in DNA fluorescence that were attributable to a process of the apoptosis. The apoptosis is activation of an endonuclease, which has relation to the intracellulle [Ca 2+] i. The study has discovered an increase of the apoptosis of the mice thymocytes following the irradiation time elongation with the He-Ne laser. The apoptosis shows an elevation of the subdiploid peak in a histogram.

关 键 词：氦氖激光 激光 细胞凋亡 胸腺细胞 亚二倍体 

分 类 号：Q631[生物学—生物物理学] Q691