3种检测方法在人间鼠疫疫情处理中的应用评价  

Analysis of Application of Three Detection Methods in Epidemic Control of Human Plague

作　　者：张宏[1] 席进孝[1] 格鹏飞[1] 吴得强[1] 郭丽民[1] 潘卫民[1] 徐大琴[1] 梁效成[1] 

机构地区：[1]甘肃省疾病预防控制中心,兰州730020

出　　处：《地方病通报》2009年第4期5-6,8,共3页Endemic Diseases Bulletin

摘　　要：目的分析ELISA，GICA和IHA（RIHA）3种方法在疫情处理中的特异性、敏感性及其在快速诊断方面的作用。方法对2起疫情的检测结果进行统计学分析。结果ELISA，GICA和IHA3种方法检测鼠疫F1抗体的阳性率分别为32．9％，2．5％和10．9％，差异有统计学意义（X2=42．28，P〈0．01）。结论在疫情处理过程中，同时使用ELISA，GICA和IHA方法检测血清中的鼠疫F1抗体，其结果快速、准确、可靠，既能快速判定疫情，又能及时发现感染者，对迅速判定疫情和有效控制疫情扩散均能起到很好作用。RIHA检验方法所需时间短、敏感性好、准确性高，是早期、快速的诊断方法。Objective To analyze specificity, sensitivity and rapid diagnosis role of ELISA, GICA and IHA [ RIHA） in epidemic control of human plague. Methods Test results of two outbreaks were analyzed by statistical methods. Results Positive rates of ELISA, GICA and IHA were 32.9% , 2.5% and 10.9%, respectively, with statistical significance （ X2 = 42.28, P 〈 0.01 }. Conclusions In epidemic control, ELISA, GICA and IHA were taken together to detect F1 antibody in human sera with rapid, accurate and reliable resuits. It can not only quickly identify the epidemic but also promptly find infected person. It can play a good role in quickly identifying epidemic situation and effectively controlling the spread. RIHA is an early, rapid diagnostic method with a short time, good sensitivity and accuracy.

关 键 词：检测方法 分析 人间鼠疫 

分 类 号：R516.8[医药卫生—内科学] R181.24[医药卫生—临床医学]