双氯芬酸钾的激光解吸离子化质谱分析  

Analysis of Diclofenac Potassium by Laser Desorption Ionization Mass Spectrum

作　　者：高松梅[1] 彭建和 盛龙生 

机构地区：[1]中国药科大学分析计算中心

出　　处：《药物分析杂志》1998年第4期226-228,共3页Chinese Journal of Pharmaceutical Analysis

摘　　要：应用激光解吸离子化／傅里叶变换质谱法进行双氯芬酸钾的正负离子质谱研究，由正负离子质谱中准分子离子及重要碎片离子的准确质量和元素组成，获取其结构信息并推测其可能的质谱裂解途径。Diclofenac potassium was studied by laser desorption ionization mass spectrometry.The spectra and mass data were determined for both positive and negative ions. The structure informations were obtained and the possible route of ion fragmentation was deduced by accurate mass measurement of quasi-molecular ions and some characteristic fragment ions.

关 键 词：激光解吸离子化 傅里叶变换质谱法 双氯芬酸钾 

分 类 号：R977.1[医药卫生—药品] R914.1[医药卫生—药学]