肝素抗凝血浆与血清的常规生化指标检测结果比较  

Heparinized Plasma Compared With Serum Samples for Measurement of Routine Biochemistry Indicators

作　　者：陈川[1] 付阳 唐书强[1] 李萍[1] 

机构地区：[1]四川大学华西医院实验医学科,四川成都610041 [2]四川大学华西临床医学院

出　　处：《预防医学情报杂志》2009年第8期694-697,共4页Journal of Preventive Medicine Information

摘　　要：目的采用不同类型的样本(肝素抗凝血浆与血清)进行常规生化指标检测,比较其结果的差异。方法在MODULAR DDP+ISE全自动生化分析仪上检测分别来自36例志愿者的肝素抗凝血浆与血清样本的29项常规生化指标,对结果进行比较分析。结果29项指标中14项指标检测结果的差异有统计学意义;但是临床可接受性分析发现,所有项目血清与血浆的检测结果差异均小于允许总误差(total error allowance,TEa),差异在TEa～1/2TEa的项目有DBIL、ALT、K;从绝对差异图上看,TP、K、P 3个项目的肝素抗凝血浆与血清检测结果间存在较大的恒定偏差。结论肝素抗凝血浆与血清用于常规生化检测时,某些指标检测结果一致性较差,如果2种类型的标本同时应用于临床,建议分别建立不同的参考范围。Objective To comparatively analyze the differences of heparinized plasma and serum samples for measurement of routine biochemistry indicators. Method A total of 29 routine biochemistry indicators were measured on an automatic biochemistry analysis instrument - MODULAR DDP ＋ ISE using heparinized plasma and serum samples from 36 objects（9 males and 27 females）. Result Comparative results of 14 indicators are statistical significant; but by clinical acceptable analysis, all the differences are less than total error allowance （TEa）. The indicators with differences more than 1/2 TEa were less than TEa were DBIL, ALT, K. The differences of indicators TP, K, P revealed significantly permanent deviations. Conclusion When using heparinized plasma and serum samples for routine biochemistry measurement, there is unsatisfied consistency in several indicators. There fore it is suggested to establish different reference value ranges.

关 键 词：肝素抗凝血浆 血清 常规生化 

分 类 号：R446.11[医药卫生—诊断学]