细辛醚衍生物的合成及其杀虫活性研究  

Study on Synthesis of Asarone Derivatives and Their Insecticidal Activities

作　　者：陈洪流[1] 赵静国[1] 谢令德[1] 王旭东[1] 潘俊[1] 陈思思[1] 

机构地区：[1]武汉工业学院生物与制药工程系,湖北武汉430023

出　　处：《化学与生物工程》2009年第8期48-50,共3页Chemistry & Bioengineering

基　　金："十一五"国家科技支撑计划项目"粮食丰产科技工程"(2006BAD02A18-01)

摘　　要：以2,4,5-三甲氧基苯甲醛为原料,经格氏反应、脱水反应合成了9种细辛醚衍生物,其中5种未见文献报道,所有化合物的结构均经1HNMR确证。杀虫活性测试结果表明,所合成化合物均具有杀虫活性,其中化合物Ⅲb杀虫活性较高。Nine asarone derivatives were synthesized from 2,4,5-trimethoxyphenyldehyde by Grignard reaction and dehydration reaction, five of which had never been reported in the literature. Their structures were confirmed by ^1 HNMR. The insecticidal activity tests showed that all the compounds exhibited some insecticidal activity,and compound Ⅲ b exhibited the highest activity.

关 键 词：细辛醚 衍生物 合成 杀虫活性 

分 类 号：TQ453.3[化学工程—农药化工]