健康体检空腹血糖受损人群临床特征分析  

ANALYSIS OF THE CLINICAL CHARACTERISTICS IN HEALTH EXAMINATION PEOPLE WITH IMPAIRED FASTING GLUCOSE

作　　者：赵辉[1] 刘颖[1] 

机构地区：[1]大连医科大学附属二院体检中心,大连116027

出　　处：《现代预防医学》2009年第16期3141-3143,共3页Modern Preventive Medicine

摘　　要：[目的]分析健康体检空腹血糖受损(IFG)人群的临床特征。[方法]采用横断面分析的方法对健康体检者1198例,根据空腹血糖状态分为糖耐量正常(NGT)组、空腹血糖受损(IFG)组、糖尿病(DM)组,比较各组间临床特征。并针对IFG组在不同年龄及不同性别的临床特征进行分析。[结果]与NGT组比较,IFG人群收缩压(SBP)、舒张压(DBP)、体重指数(BMI)、甘油三酯(TG)、总胆固醇(TC)及低密度脂蛋白-胆固醇(LDL-C)明显增高;高密度脂蛋白-胆固醇(HDL-C)明显减低;血脂紊乱、高血压、肥胖/超重患病率、存在3个及以上危险因素比率明显增高。与DM组比较,IFG组SBP、DBP升高程度不如DM组显著。IFG组随着年龄增高SBP、LDL-C明显增高;老年人群较青年人群血脂紊乱及高血压患病率增高。IFG组男性在DBP、TG及肥胖/超重患病率显著高于女性。[结论]IFG时期已存在血脂代谢紊乱、肥胖/超重、血压升高趋势;IFG人群在年龄和性别上临床代谢特征不同。[Objective] To analyze the clinical characteristics in health examination people with impaired fasting glucose. [Methods] A cross-sectional analysis of clinical characteristics was conducted in 1198 health examination people. According to fasting plasma glucose（FPG） ,the subjects were divided into 3 groups：normal glucose tolerance（NGT） ,impaired fasting glucose（IFG） and diabetes mellitus（DM） ,and the clinical characteristics of the above subcategories were analyzed. Meanwhile,the clinical characteristics of the IFG subcategory in the age groups and the sex groups were Compared. [Results] Compared with the NGT group, the IFG group had higher systolic blood pressure （SBP）, diastolic blood pressure （DBP）, body mass index （BMI）, triglyceride （TG）, total cholesterol （TC） and low density lipoprotein cholesterol （LDL-C）, and lower high density lipoprotein cholesterol （HDL-C） . The prevalence of lipid disorder, hypertension, obesity/overweight, and the ratio of three or more risk factors were statistically higher than those in the NGT group. The IFG group had lower SBP and DBP than the DM group. With the increasing of age. the levels of SBP and LDL-C increased in IFG group. Compared with youth group, the old age group had more serious lipid disorder and hypertension. In IFG group DBP, TG and obesity/over- weight were significantly increased in male subjects. [Conclusion] The results show that lipid disorder, obesity/overweight and increased blood pressure exist in the IFG stage. The clinical characteristics of age and sex are significantly different in IFG group.

关 键 词：空腹血糖受损 糖尿病 临床特征 

分 类 号：R194.3[医药卫生—卫生事业管理]