妊娠高血压综合征患者瘦素胰岛素及C肽的相关性研究  

Study on relationship among pregnancy-induced hypertension and plasma leptin,insulin and C-peptide Levels

作　　者：赵惠[1] 

机构地区：[1]临沂市人民医院妇产房,山东临沂276000

出　　处：《现代医药卫生》2009年第17期2606-2607,共2页Journal of Modern Medicine & Health

摘　　要：目的:探讨妊娠高血压综合征(妊高征)与瘦素、胰岛素、C肽的关系。方法:采用放射免疫分析法,测定62例妊高征孕妇(妊高征组)和62例正常孕妇(对照组)血浆瘦素、胰岛素、C肽的含量。结果:妊高征组瘦素、胰岛素、C肽水平与对照组比较差异有显著性(t=7.26～17.31,P<0.01),中、重度妊高征组血浆瘦素、胰岛素、C肽与轻度妊高征组比较,差异有显著性(F=3.80～13.89,q=3.53～10.36,P<0.05、0.01)。结论:高瘦素和高胰岛素血症在妊高征的发病中可能起重要作用。Objective ：To investigate the relationship among pregnancy-induced hypertension（PIH） and plasma leptin ,insulin and C- peptide levels.Methods：Blood samples from 62 PIH patients and 62 mormal pregnant women were collected and plasma liptin ,insulin and C-peptide were detected by radloimmunossay.The results were statistically analyzed.Results：The PIH group differed significantly from the control group in the levels of leptin,insulin and C-peptide （t=7.14-18.77 ,P〈0.01）.The patients with severe or moderate PIH differed significantly from those with mild PIH in the levels of liptin,insulin and C-peptide （F=3.80-13.89,q=3.53-10.36,P〈0.05,0.01）. Conclusion： High plasma leptin and insulinemia may play an important role in the development of PIH.

关 键 词：瘦素 胰岛素 C肽 妊娠高血压综合征 

分 类 号：R71[医药卫生—妇产科学]