老年2型糖尿病患者血清超敏C反应蛋白与糖尿病肾病相关性分析  

Analysis of the association between high-sensitive C-reactive protein and diabetic nephropathy in elderly patients with type 2 diabetes mellitus

作　　者：庄文翔[1] 申志祥[2] 张鹏翎[1] 

机构地区：[1]江苏省省级机关医院保健科,江苏省南京市210024 [2]江苏省省级机关医院肾科,江苏省南京市210024

出　　处：《实用老年医学》2009年第4期296-298,共3页Practical Geriatrics

摘　　要：目的分析老年2型糖尿病(T2DM)患者血清超敏C反应蛋白(hsCRP)与糖尿病肾病(DN)的相关性及临床意义。方法72例老年T2DM患者根据尿白蛋白排泄率(UAER)分为:正常白蛋白尿组(A组)30例,微量白蛋白尿组(B组)22例,临床白蛋白尿组(C组)20例;另设健康对照组(D组)30例。采用免疫透射比浊法测定各组血清hsCRP浓度,比较T2DM各组与对照组的hsCRP水平。结果T2DM各组血清hsCRP水平较对照组明显升高,且随UAER的增高而升高。结论hsCRP为DN的发病危险因素之一,且随DN病程的进展,hsCRP水平逐渐升高。Objective To analyze the association between high-sensitive C-reactive protein （hsCRP） and diabetic nephropathy （DN） in elderly patients with type 2 diabetes mellitus （T2DM）. Methods According to the results of urinary albumin excretion rate （UAER） ,72 cases of T2DM were divided into normal albumin urinary group （A） , micro albumin urinary group （ B ） , and clinical albumin urinary group （ C ）. Thirty healthy subjects were enrolled as control （D）. The blood levels of hsCRP of all groups were measured. Results There was significant difference in hsCRP level between group A, B, C and control group. The level of hsCRP was increased with the increase of UAER. Conclusions hsCRP is one of the risk factors for DN. Increased hsCRP might be related to the progression of DN.

关 键 词：老年人 2型糖尿病 超敏C反应蛋白 糖尿病肾病 

分 类 号：R587.2[医药卫生—内分泌]