高血压和肥胖对糖尿病视网膜病变的影响  

The Effect of Hypertension and Obesity on Diabetic Retinopathy

作　　者：楼继先[1] 曹永葆[1] 张志勇[1] 李小燕[1] 严学军[1] 

机构地区：[1]浙江医院眼科,浙江杭州310013

出　　处：《心脑血管病防治》2009年第4期257-258,共2页CARDIO-CEREBROVASCULAR DISEASE PREVENTION AND TREATMENT

摘　　要：目的:探讨糖尿病视网膜病变与高血压和肥胖的临床关系。方法:将286例2型糖尿病患者分别分为高血压组、非高血压组;肥胖组、非肥胖组,分别探讨肥胖及高血压对糖尿病视网膜病变发生和发展的影响,分析糖尿病视网膜病变与高血压和肥胖的临床关系。结果:高血压组发生糖尿病视网膜病变明显高于非高血压组,两组比较差异有统计学意义(χ2=10.07,P<0.01);肥胖组发生糖尿病视网膜病变明显高于非肥胖组,两组比较差异有统计学意义(χ2=4.45,P<0.05)。结论:糖尿病合并高血压及肥胖将增加糖尿病视网膜病变的发生和发展,因此糖尿病患者在严格控制血糖的同时应控制血压和减轻体重。Objective To explore the clinic relationship between diabetic retinopathy（DR） and hypertension and obesity. Methods 286 cases of type 2 diabetes mellitus were divided into hypertension group and non-hypertension group. The cases were also divided into obesity group and non-obesity group according to body mass index. The effects of hypertension and obesity on the development and progression of DR were analyzed. Results The incidence of DR in hypertension group was significantly higher than in non-hyper- tension group （ P 〈 0.01 ）. The incidence of DR in obesity group was markedly higher than in non-obesity group （ P 〈 0.05）. Condusions Hypertension and obesity would increase the risk of development and progression of DR in diabetes mellitus. Therefore strict control of blood pressure, the level of blood sugar and boy weight are equally important in diabetic patients.

关 键 词：2型糖尿病合并高血压 糖尿病视网膜病变 肥胖 大血管病变 慢性疾病 粥样硬化 血管壁 患病率 

分 类 号：R544.1[医药卫生—心血管疾病] R587.2[医药卫生—内科学] R589.2[医药卫生—临床医学] R774.1