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作 者:喻迪标[1]
机构地区:[1]湖南省湘潭市第一人民医院,湖南湘潭411101
出 处:《医学临床研究》2009年第8期1410-1411,共2页Journal of Clinical Research
摘 要:【目的】探讨幽门螺杆菌(HP)感染根除失败的再治疗方法。【方法】70例HP感染根除失败患者随机分为A和B组,以雷贝拉唑、莫西沙星和克拉霉素组成方案,分为7d疗程组(A组,n=35)和14d疗程组(B组,n=35)进行对比研究。【结果】A组根除率为74.29%(26/35),B组为94.29%(33/35),两组比较差异有统计学意义(χ2=5.2851,P〈0.05)。A和B组不良反应发生率分别为14.29%(5/35),25.71%(9/35),两组比较差异没有统计学意义(χ2=1.4286,P〉0.05)。【结论】以雷贝拉唑、莫西沙星和克拉霉素组成方案作为HP感染根除失败的再治疗方案有较高的根除率,且用药14d的疗效更佳。[Objective] To explore the re-treatment of helicobacter pylori(HP) infection after eradication failure. [Methods] The regimens consisted of rabeprazole, moxifloxaein and clarithromycin triple therapies. Seventy patients with HP eradication failure were randomized into the group A ( n=35, for 7 days) and B ( n=35, for 14 days).[Results] The eradication rates of group A and 13 were 74.29%(26/35) and 94.29%(33/ 35), respectively(χ2=5. 2851, P〈0.05). The incidence rates of adverse effects of group A and B were 14.29% (5/35) and 25. 71% (9/35), respectively(χ2=1. 4286, P〉0.05).[Conclusion]The eradication rate of helicobacter pylori eradication with rabeprazole, moxifloxacin and clarithromycin triple therapies after helicobacter pylori eradication failure is relatively high. And the administration for 14 days has better effect.
分 类 号:R377[医药卫生—病原生物学]
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