非典型病原体所致社区获得性肺炎的实验研究  

An experimental study of atypical pathogens leading to community acquired pneumonia

作　　者：廖晚珍[1] 彭卫华[1] 胡雪飞[1] 孙爱娣[1] 余阳[1] 温桂兰[2] 陈国华[2] 

机构地区：[1]南昌大学第一附属医院检验科,江西南昌330006 [2]南昌大学第一附属医院呼吸科,江西南昌330006

出　　处：《实验与检验医学》2009年第4期339-340,共2页Experimental and Laboratory Medicine

基　　金：江西省卫生厅基金资助(合同编号:041052)

摘　　要：目的探讨成人社区获得性肺炎(CAP)非典型病原体的构成及有关问题,为临床治疗提供依据。方法收集121例CAP患者急性期和恢复期血清,采用微量颗粒凝集(MAG)法检测肺炎支原体,微量免疫荧光(MIF)法检测肺炎衣原体,间接荧光免疫(IFA)法检测嗜肺军团菌,酶免疫测定(EIA)法检测军团菌尿抗原。结果121例CAP患者共检出非典型病原体28例,其中肺炎支原体19例,是最常见的非典型病原体,其后依次是肺炎衣原体6例,嗜肺军团菌3例,3例阳性病例中军团菌尿抗原检测也是阴性。121例CAP中绝大多数为单一病原体感染,混合感染仅6例。结论肺炎支原体是CAP中同时也是非典型病原体中最多的一种病原体,肺炎衣原体所占比例较高,而嗜肺军团菌检出较少。Objective To study the atypical pathogens leading to community acquired pneumonia （CAP）, for the treatment. Methods Collecting 121 serum samples of CAP with acute phase and recovery phase, using MAG method examined mycoplasma pneumoniae, MIF examined chlamydia pneumoniae, IFA examined legionella pneumolhilia and EIA examined urinogic antigen of legionella. Results Of 121 cases of CAP, 28 cases with atypical pathogens were examined, including 19 cases of mycoplasma pneumoniae, next 6 cases of chlamydia pneumoniae and 3 cases of legionella pneumolhilia with negtive of urinogic antigen of legionella. Almost cases showed single pathogen infection, but 6 cases were mixed infection. Conclusions Mycoplasma pneumoniae is the most atypical pathogen in CAP. Chlamydia pneumoniae showed a higher ratio, but few legionella pneumolhilia.

关 键 词：社区获得性肺炎 非典型病原体 肺炎支原体 肺炎衣原体 嗜肺军团菌 

分 类 号：R446.5[医药卫生—诊断学]