(硫杂)杯[4]芳烃缩氨基(硫)脲(桥联)衍生物的合成  

Syntheses of (Thia)calix[4]arene (Thio)semicarbazone(-bridged) Derivatives

作　　者：唐富胜[1] 杨发福[1] 黄智胜[1] 洪碧琼[1] 郭红玉[1] 

机构地区：[1]福建师范大学化学与材料学院,福州350007

出　　处：《有机化学》2009年第8期1278-1281,共4页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(No.20402002);福建省自然科学基金(No.2009J01019);福建省高校新世纪优秀人才支持计划资助项目

摘　　要：对叔丁基(硫杂)杯[4]芳烃-1,3-二醛基衍生物4a和4b与苯基氨基硫脲进行"1+2"缩合反应,合成了杯[4]芳烃缩氨基硫脲衍生物5a和5b,产率为84%和85%.化合物4a和4b与1,6-己基双氨基脲发生"1+1"缩合反应,合成了杯[4]芳烃双缩氨基脲桥联衍生物6a和6b,产率为83%和80%.新化合物的结构与构象经元素分析、质谱、核磁共振谱等表征证实.（Thia）calix[4]arene thiosemicarbazone derivatives 5a and 5b were synthesized by ＂1 ＋2＂ condensation of 1,3-bis[2-（p-formylphenyloxy）ethyloxy]-p-tert-butylcalix[4]arene 4a and 4b with 1-phenylthiosemicarbazide in yields of 84% and 85%, respectively. （Thia）calix[4]arene semicarbazone-bridged derivatives 6a and 6b were prepared by reacting compounds 4a and 4b with 1,6-hexylenebis（1-semicarbazide） in ＂1 ＋ 1＂ condensation in yields of 83% and 80%, respectively. The structures and conformations of the new compounds were characterized by elemental analyses, ESI-MS, 1H NMR, etc.

关 键 词：芳烃 缩氨基脲 合成 桥联 

分 类 号：O625.7[理学—有机化学]