机械通气对慢性阻塞性肺疾病患者肝、肾功能的治疗意义  

Recognition the Changes of Function of Kidney and Liver on Chronic Obstructive Pulmonary Disease (COPD) before and after Therapy with Mechanical Ventilation

作　　者：程青虹[1] 崔玉静[1] 黄霞[1] 李小芳[1] 高敏[1] 

机构地区：[1]新疆石河子大学医学院第一附属医院,石河子832008

出　　处：《中国医药导刊》2009年第8期1277-1278,共2页Chinese Journal of Medicinal Guide

摘　　要：目的:分析慢性阻塞性肺疾病(COPD)患者行机械通气前后肾、肝功能的变化,评价机械通气对COPD患者的治疗意义。方法:搜集56例本院已经确诊为COPD且转入ICU行机械通气的患者的资料.按给氧浓度分为低浓度组(≤30%)、中浓度组(31%～50%)和高浓度组(51%～100%),统计3组COPD患者机械通气前后血BUN、CR、AST、ALB、ALT等结果,分析通气前后患者肝、肾功能的改变。结果:低浓度组CR统计P值<0.05有统计学意义,中浓度组CR、ALB统计P值≤0.05有统计学意义。其余指标P值均>0.05无统计学意义。结论:机械通气不能在一定程度上明显改善COPD患者的肾、肝功能。Objective： Observing changed of kidney and liver function of COPD patients before and after mechanical ventilation.So evaluate the significance of mechanical ventilation on COPD. Method： Collected 56 ICU patients therepied with mechanical ventilation who have been diagnosed COPD, 56 cases of COPD patients were divided into three groups by mechanical ventilation oxygen concentration, low concentration （〈 30 %）,middle concentration （31%～50 %） and high concentration （51%～ 100 %）, determination three groups of patients＇ BUN, UA, AST, ALB, ALT of blood before and after mechanical ventilation to observe the changes of COPD patients kidney and liver function before and after mechanical ventilation. Result： In low concentration CR P 〈0.05 is significant ,in the middle concentrations group, CR and ALB statistics P 〈0.05 is significant, the remaining indicators P〉0.05 is not statistically significant. Conclusion： mechanical ventilation can not significantly improve COPD patients＇ kidney and liver function to a certain extent.

关 键 词：机械通气 慢性阻塞性肺疾病 肾功能 肝功能 

分 类 号：R563.9[医药卫生—呼吸系统]