^(18)F-FDG PET/CT在肺部占位性病变诊断中的价值  

^(18)F-FDG PET/CT in Diagnosing Pulmonary Occupying Lesions

作　　者：杨春山[1] 刘靖[2] 陈宪英[1] 马庆和[1] 石华铮[1] 邓侃[1] 黄志强[1] 陈兴龙[1] 毛德金[1] 李廷[1] 

机构地区：[1]中国人民解放军第四五五医院PET-CT高端体检中心,淮海西路338号上海200052 [2]第二军医大学附属长征医院影像科

出　　处：《中国医学计算机成像杂志》2009年第4期366-371,共6页Chinese Computed Medical Imaging

基　　金：上海市基础重点基金资助(编号:06JC14088)

摘　　要：目的:探讨18F-FDGPET/CT在诊断肺部占位性病变中的价值。方法:对100例肺部占位性病变进行回顾性分析,比较PET/CT与PET及CT的诊断效度、不同大小肿瘤的SUV、不同病理类型肺癌的SUV。结果:①PET/CT的灵敏度、阴性预测值、准确率优于CT(P<0.01),PET/CT的特异度优于PET(P<0.05)。②依据肿瘤大小分为<3cm、3～5cm、>5cm组,应用单向方差分析对比不同组间SUV,3组间SUV均有差异,P<0.01。各组间SUV两两比较,发现小于3cm组SUV<3～5cm组SUV<5cm以上组SUV。③鳞癌组与腺癌组SUV无显著差异(P=0.821,P>0.05)。结论:18F-FDGPET/CT在诊断肺部占位性病变中将PET代谢学特征密切结合CT的形态学表现,可大大提高各项诊断效率,达到优势互补的目的。Purpose： To evaluate the value of ^18F- FDG PET/CT in diagnosing pulmonary occupying lesions. Methods： One hundred cases of pulmonary occupying lesions were retrospectively analyzed. The diagnosis validity of PET, CT, PET/ CT; the SUV of different size occupying lesions; and the SUV of different pathology occupying lesion were compared respectively. Results： ①The sensitivity , predictive value and accurate rate of PET/CT were higher than those of CT（P 〈 0.01）, the specificity of PET/ CT was higher than that of PET（P 〈 0.05） . ② According to the size of tumor, cases were divided into 3 groups： 〈 3cm group, 3 - 5cm group and 〉 5cm group. SUV of different groups were compared by one - way analysis of variance. The SUV of 〈 3cm group was lower than that of 3 - 5cm group and 〉 5cm group. The SUV of 3 - 5cm group was lower than that of 〉 5cm group.③ There were no significant difference between the SUV of squamous carcinoma and that of adenocarcinoma（P = 0. 821, P 〉 0.05） . Conclusion： Combined biological metabolism character with morphologic appearance, PET/CT can improved the diagnosis validity consumedly.

关 键 词：体层摄影术 发射型计算机 体层摄影术 X线计算机 肺肿瘤 肺占位 

分 类 号：R817.4[医药卫生—影像医学与核医学] R816.4[医药卫生—放射医学]