可生物降解的聚乳酸弹性体的性能研究  

STUDY ON PROPERTIES OF BIODEGRADABLEPOLYLACTIDE ELASTOMERS

作　　者：宋谋道[1,2] 朱吉亮 张邦华[1,2] 郝广杰 张莹[1,2] 赵英奇 范玉玲[1,2] 杨世强[1,2] 

机构地区：[1]南开大学高分子化学研究所吸附分离功能高分子材料国家重点实验室 [2]天津第一中心医院

出　　处：《高分子学报》1998年第4期393-398,共6页Acta Polymerica Sinica

摘　　要：对制备的聚乳酸（聚醚）酯型聚氨酯弹性体进行了动态力学、力学性能和降解性能的测试．结果表明，弹性体的强度和弹性都较好，它们受交联度、ＰＥＧ含量和ＰＥＧ分子量的影响．该弹性体的降解速度较快．降解过程中存在自催化效应，而且是从表面开始由表及里逐渐降解的．但材料降解过程中也会出现内部降解较快的现象．动物实验表明，该弹性体是一种能满足尿道支撑管要求的有实际应用价值的材料．The mechanical properties and degradable properties of PLA PEG/PU elastomers were determined by DMA,stress strain and degradable experiment.The result shows that the tensile strength and the elongation decreased,as the content and the Mw of PEG increased.The degradable time increased with the Mw of PEG increased,but decreased with the content of PEG increased.The elastomer was degraded mainly from the surface,but sometime faster in the inner in urine.There was an auto acceleration effect in the degrading process of PLA PEG/PU elastomer.The animal experimental result shows that the elastomer is fit to Urethra Supporting.

关 键 词：聚氨酯 弹性体 尿道支撑材料 聚乳酸酯型 

分 类 号：R318.08[医药卫生—生物医学工程]