停流法研究Cu(Ser)_2及Cu(Gly-Gly)_2催化O_2^(·-)歧化反应动力学  

The Kinetics Study on Dismutation of Superoxide Catalyzed by Cu(Ser) 2 and Cu(Gly Gly) 2 by Using Stopped flow Method

作　　者：谢英[1] 金虬[1] 李大珍[1] 高盘良[2] 自俊青 

机构地区：[1]北京师范大学化学系 [2]北京大学化学系 [3]大理师范学院化学系

出　　处：《高等学校化学学报》1998年第8期1288-1291,共4页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金

摘　　要：采用停流法对ｐＨ＝７．８的磷酸盐缓冲液体系中丝氨酸铜Ｃｕ（Ｓｅｒ）２和甘氨酰甘氨酸铜Ｃｕ（Ｇｌｙ－Ｇｌｙ）２催化超氧阴离子自由基Ｏ·－２歧化反应的动力学进行了研究，求得不同温度下的催化速率常数ｋｃａｔ、反应级数ｎ、活化能Ｅａ及指前因子Ａ，初步探讨了Ｃｕ（Ｓｅｒ）２和Ｃｕ（Ｇｌｙ－Ｇｌｙ）２催化Ｏ·－２歧化反应机理，证实了第一步反应为整体反应过程的速控步骤．In order to estimate the activities of natural SOD and the analogue of SOD on dynamics, the kinetics of Cu(Ser) 2 and Cu(Gly Gly) 2 catalyzed the dismutation of superoxide were studied at pH=7.8 by using stopped flow method. The rate constants k cat , reaction order n , activation energy E a and Arrhenius equation were obtained. the reaction mechanism was probed, and it was proved that the first step of the reaction was the determining step.

关 键 词：阴离子 SOD模拟物 催化剂 歧化反应 超氧自由基 

分 类 号：O613.3[理学—无机化学] O643.36[理学—化学]