供氧加温湿化联合沐舒坦雾化对COPD急性发作期患者氧疗效果的影响  

The Combined Effects of Warming Humidification Oxygen Therapy and Oxygen Atomizing Inhalation of Mucosolvan in Chronic Obstructive Pulmonary Disease During Exacerbated Period

作　　者：李石荣[1] 陈喻萍[1] 秦春燕[1] 卓宋明[1] 刘金举[1] 

机构地区：[1]深圳市龙岗中心医院内科广东深圳,518116

出　　处：《护理学杂志》2009年第17期29-31,共3页

基　　金：深圳市龙岗区科技局2008年度科技计划项目(深龙科[2008]24号)

摘　　要：目的探讨供氧加温湿化联合沐舒坦雾化治疗慢性阻塞性肺疾病(COPD)急性发作期患者的氧疗效果。方法将84例COPD急性发作期患者按随机数字表法分为观察组(44例)和对照组(40例)。观察组采用多功能氧气湿化器对氧气加温湿化,同时采用氧气驱动式雾化吸入沐舒坦(每天3次);对照组用传统的浮标式氧气吸入器持续吸氧。观察两组患者心率、呼吸、血气分析结果、痰液黏稠度、气喘缓解时间和痰鸣音消失时间。结果观察组动脉血氧分压显著提高,心率、呼吸和二氧化碳分压显著降低(均P<0.05);气喘缓解时间、痰鸣音消失时间显著短于对照组,痰液黏稠度显著优于对照组(均P<0.01)。结论供氧加温湿化联合沐舒坦雾化可提高COPD急性发作期患者的氧疗效果,且患者感觉舒适,痰液稀释容易排出,不易发生刺激性呛咳反应,患者易接受。Objective To test the combined effects of warming humidification oxygen therapy and oxygen atomizing inhalation of mucosolvan in chronic obstructive pulmonary disease （COPD） during exacerbated period. Methods A total of 84 patients with acute onset of COPD were enrolled and randomly divided into an observational group （44 cases） and a control group （40 cases）. The observational group were treated with warming humidification oxygen therapy and oxygen atomizing inhalation of mucosolvan three times a day. The control group were treated with traditional oxygen therapy. The heart and breath rate, findings of blood gas analysis including oxygen percent saturation （SaO2）, oxygen partial pressure （PaO2） and partial pressure of carbon dioxide （PaCO2） were recorded. The sputum thickness, duration of wheezing and sputum wheezy sound of the 2 groups were compared. Results There were significant differences in the values of PaO2, PaCO2, heart and breath rates, duration of wheezing and sputum wheezy sound between the 2 groups （P〈0.05 ,P〈0.01）. Conclusion Warming humidification oxygen and oxygen atomizing inhalation of mucosolvan can effectively improve the treatment result of COPD. Patients feel comfortable and the sputum is easier to cough up. No irritating coughing is induced and the method is widely accepted by the patients.

关 键 词：慢性阻塞性肺疾病 氧疗 沐舒坦 加温湿化 氧气雾化吸入 

分 类 号：R47[医药卫生—护理学] R459.6[医药卫生—临床医学]