老年患者术后认知功能障碍发生率及相关因素的多中心研究  

Multi-center clinical study on morbidity and related factors of postoperative mental and cognitive disorder in the elderly

作　　者：李兴[1] 闻大翔[1] 陈杰[1] 李立志[2] 万燕杰 刁枢[4] 洪涛[1] 杭燕南[1] 

机构地区：[1]上海交通大学医学院附属仁济医院麻醉科,200001 [2]上海市浦东新区人民医院 [3]上海市公利医院 [4]上海市第七人民医院

出　　处：《临床麻醉学杂志》2009年第8期652-654,共3页Journal of Clinical Anesthesiology

基　　金：上海市浦东新区科技专项基金项目(项目编号:PKJ2004-13)

摘　　要：目的研究老年手术患者术后认知功能障碍(POCD)的发生率及相关影响因素。方法对上海4所医院513例老年非心脏手术患者(N组)应用简易智能量表进行POCD评定,并与29例非体外循环下行冠脉搭桥术老年患者(C组)POCD评定结果作比较。结果N组患者POCD发生率为10.5%,明显低于C组的27.6%。术前合并糖尿病及教育水平较低是其相关影响因素。结论老年非心脏手术患者比心脏手术患者POCD的发生率低,术前合并糖尿病及教育水平较低是非心脏手术患者发生POCD的重要影响因素。Objective To analyze the morbidity and related factors influencing postoperative cognitive disorder（POCD） in elder patients underwent non-cardiac and cardiac surgery. Methods POCD was evaluated with mini-mental state examination（MMSE） in 513 elder patients [（73.3±5.9） years old, group N] underwent non-cardiac surgery in Shanghai 4 hospitals, which was compared with that in 29 patients[（69.2± 10.3） years old, group C）] underwent off-pump coronary artery bypass grafting（OPCABG）. Results The morbidity of POCD was significantly lower in group N than that in group C（10. 5% vs. 27.6%）. The relatively lower educational level and diabetes are the factors influencing the morbidity of POCD. Conclusion The morbidity of POCD is higher in elder patients underwent cardiac surgery than that underwent non-cardiac surgery. The relatively lower educational level and diabetes are the factors influencing the morbidity of POCD.

关 键 词：术后认知功能障碍 老年 

分 类 号：R619[医药卫生—外科学] R614[医药卫生—临床医学]