番鸭呼肠孤病毒B3株感染对雏番鸭细胞免疫功能的影响  

Effects of infection with muscovy duck reovirus isolate B3 on the cellular immunity function of muscovy duck

作　　者：王全溪[1] 赵丽娟[1] 苏凤[1] 吴宝成[1] 李国平[1] 

机构地区：[1]福建农林大学动物科学学院,福建福州350002

出　　处：《福建农林大学学报（自然科学版）》2009年第4期380-383,共4页Journal of Fujian Agriculture and Forestry University:Natural Science Edition

基　　金：福建省自然科学基金资助项目(20006J0298;2002F003)

摘　　要：番鸭感染番鸭呼肠孤病毒后,在感染早期(15 d内),外周血淋巴细胞转化率比对照显著下降(P<0.01),外周血T淋巴细胞ANAE阳性率比对照显著下降(P<0.01),IL-2含量也比对照组显著下降(P<0.01);但在感染后期(特别是感染后20 d)各指标均有所回升,但仍显著低于对照.由此可见,番鸭呼肠孤病毒感染早期机体细胞免疫功能受到严重影响,感染后期功能逐渐恢复.The results showed that the lymphocytes transformation rate of the ducks infected by muscovy duck reovirus isolate B3 was significantly less than that of control group （P 〈0.01 ）, T cells ANAE positive rate in peripheral blood of experiment groups was significantly less than that of control group （P 〈 0.01 ）, and the concentration of interleukin-2 in peripheral blood of experiment groups was significantly less than that of control group （P 〈 0.01 ） at the earlier stage of infection. At the later stage of infection （ especially after infection of 20 d）, above indexes were all upturned, but still less than control group. So at the early stage of infection with muscovy duck reovirus, the virus affected the cellular immune function of muscovy duck, and at the later stage of infection the cellular immune function recovered.

关 键 词：番鸭呼肠孤病毒 细胞免疫 番鸭 感染 

分 类 号：S852.65[农业科学—基础兽医学] S852.4[农业科学—兽医学]