益气活血汤治疗颈动脉硬化斑块疗效观察  

The clinical research of treatment of carotid arteriosclerosis plaque with Yiqihuoxue decoction

作　　者：陈文实[1] 张锋[2] 李仁柱[3] 

机构地区：[1]安徽省蚌埠市第三人民医院中西医结合科,233000 [2]安徽省蚌埠市第三人民医院超声科,233000 [3]安徽省蚌埠市第三人民医院影像中心,233000

出　　处：《蚌埠医学院学报》2009年第8期677-679,共3页Journal of Bengbu Medical College

基　　金：安徽省蚌埠市科技局立项课题(蚌科【2008】43号)

摘　　要：目的:探讨益气活血汤在治疗颈动脉硬化斑块中的临床疗效。方法:将颈动脉硬化斑块形成的58例患者随机均分为两组,对照组给予常规降压、降血糖及抗血小板聚集治疗,治疗组在此基础上给予益气活血汤煎剂口服,每天2次,每次200 ml,8周后记录颈动脉管腔直径、内-中膜厚度、斑块大小及血液流变学改变。结果:治疗组治疗后血液流变学均有明显改善(P<0.01);颈动脉内-中膜明显变薄,颈动脉硬化斑块缩小或消失,与对照组差异均有统计学意义(P<0.01)。结论:益气活血汤治疗颈动脉硬化斑块疗效显著。Objective： To study the therapeutic effect of Yiqihuoxue decoction on treatment of carotid arteriosclerosis plaque. Methods：Fifty-eight patients with carotid arteriosclerosis plaque were randomly divided into two groups, these cases in control group were given routine depressurization, decreasing the concentration of glucose and anti-platelet aggregation treatments, while Yiqihuoxue decoction was taken orally twice a day for these cases who belong to treatment group, 200 ml every time. The carotid artery diameter, thickness of intima media, plaque size and the changes of haemorheology were recorded after 8 weeks. Results： Compared with pretreatment, the changes of haemorheology were obviously improved in treatment group, intima media in carotid artery was obviously thinner. Plaque in carotid angioselerosis was smaller or even disapeared. There was a statistical significance of efficiency variance in contrast to the control group （ P 〈 0. 01 ）. Conclusions ： Yiqihuoxue decoction can play an effective role on treatment of carotid arteriosclerosis plaque.

关 键 词：颈动脉疾病 动脉粥样硬化 益气活血汤 

分 类 号：R543.4[医药卫生—心血管疾病]