肺心病患者急性发作期血浆D二-聚体及C反应蛋白测定的临床意义  

Clinical significance of the levels of serum D-dimer and C reative protein in patients with pulmonary heart disease

作　　者：孙军[1] 高忠和[1] 刘刚[1] 胡恩贝[1] 

机构地区：[1]安徽省蚌埠市第三人民医院呼吸内科,233000

出　　处：《蚌埠医学院学报》2009年第8期691-692,共2页Journal of Bengbu Medical College

摘　　要：目的:探讨慢性肺源性心脏病(肺心病)患者急性发作期血浆D-二聚体(D-dimer,DDR)和C反应蛋白(C reactiveprotein,CRP)变化的临床意义。方法:采用全自动生化分析法测定肺心病患者(41例)与健康对照组(30名)血浆DDR及CRP水平。结果:肺心病患者血浆DDR及CRP浓度均较健康对照组明显增高(P<0.01)。结论:肺心病患者CRP浓度增高提示肺部感染病理生理过程。DDR反映肺心病患者血液高凝状态,有助于肺部微小血栓的诊断。Objective：To explore the clinical significance of D-dimer （DDR） and Creative protein （CRP） in patients with chronic pulmonary heart disease. Methods：The levels of DDR and CRP were measured in the plasma of 41 patients with chronic pulmonary heart disease and 30 healthy controls. Results： The plasma levels of DDR and CRP were significantly different between the patients with chronic pulmonary heart disease and the healthy controls （ P 〈 0. 01 ）. Conclusions： The increase of serum CRP indicates pathophysiology of pneumonia. Serum DDR reveals the patients＇ hypercoagulabale state and is of helps to the diagnosis of microthromb in the lung.

关 键 词：肺心病 D二-聚体 C反应蛋白 

分 类 号：R541.5[医药卫生—心血管疾病]