两性霉素B治疗肺部真菌感染的疗效观察  

CLINICAL EFFECT OF AMPHOTERICIN B ON PATIENTS WITH FUNGUS INFECTION OF LUNG

作　　者：杨炜[1] 陈力[2] 

机构地区：[1]成都市第六人民医院呼吸内科,成都610051 [2]成都铁路中心医院老年科

出　　处：《现代预防医学》2009年第15期2987-2988,共2页Modern Preventive Medicine

摘　　要：[目的]探讨两性霉素B治疗肺部真菌感染的临床疗效。[方法]将60例肺部真菌感染患者随机分为观察组(35例)和对照组(25例),观察组采用两性霉素B治疗,对照组采用酮康唑治疗,疗程结束后比较两组的临床治疗效果。[结果]观察组有效率为85.71%,对照组有效率为48.00%,观察组疗效显著优于对照组(P﹤0.05)。[结论]两性霉素B治疗肺部真菌感染临床疗效显著,安全性高,值得临床应用推广。To explore the clinical curative effect and safety of amphotericin B on patients with fungus infection of lung. [Methods] 60 patients with fungus infection of lung were divided randomly into the intervention group （35 cases） and the control group （25 cases）, the intervention group was treated with amphotericin B, while the control group was treated with ketoconazole, and then compared the effect of them. [Results] Ttotal effectiveness rate was 85.71% in the intervention group, 48.00% in the control group, which showed that the former were better than the latter （P﹤0.05）. [Conclusion] Amphotericin B is evidently effective and highly safe for the treatment of patients with fungus infection of lung, and is worthy of being recommended in clinical practice.

关 键 词：两性霉素B 酮康唑 肺部真菌感染 

分 类 号：R978.5[医药卫生—药品]