2-乙酰基芴的合成新工艺  

Study on the New Technology for Preparation of 2-Acetylfluorene

作　　者：郑昕[1] 刘保霞[1] 李江涛[2] 赵文献[1] 

机构地区：[1]商丘师范学院,河南商丘476000 [2]河南省科学院化学研究所,郑州450003

出　　处：《河南科学》2009年第9期1066-1068,共3页Henan Science

基　　金：河南省国际科技合作资助项目(0811020600);河南省教育厅自然科学基金(2008A150019)

摘　　要：以工业芴和乙酰氯为原料、经Friedel-Crafts反应高效率地得到了2-乙酰基芴,具有操作简便、条件温和、产率高、选择性好等优点,为合成2-乙酰基芴提供了一种有效的方法;讨论了溶剂、催化剂、温度等对反应的影响,并对产品进行了FT-IR,1H NMR验证.A convenient and efficient procedure is described for the preparation of 2-acetylfluorene using fluorene and acetyl chloride as the base material, AlCl3 as the catalyst by Friedel-Crafts reaction. The method has several advantages such as simple operation, mild reaction conditions and high selectivity etc. The influece of solvent, catalyst and temperature on the reaction is also discussed. Its structure is characterized by FT-IR, ^1H NMR.

关 键 词：芴 酰基化 2-乙酰基芴 

分 类 号：O623.622[理学—有机化学] O625.153[理学—化学]