老年慢性阻塞性肺疾病与骨质疏松症的相关性研究  

Study of relationship about chronic obstructive pulmonary disease in senior and osteoporosis

作　　者：杨菊[1] 张燕祺[1] 马蕾[1] 刘彬[1] 莫艳萍[1] 

机构地区：[1]昆明医学院第一附属医院干疗科,650032

出　　处：《中国老年保健医学》2009年第4期31-33,共3页Chinese Journal of Geriatric Care

基　　金：云南省教育厅课题

摘　　要：目的通过测定昆明地区老年男性慢性阻塞性肺疾病(COPD)患者骨密度、肺功能和血气分析的变化,探讨老年COPD与骨质疏松症的相关性。方法用双能X线吸收测定仪(DEXA)测定32例老年COPD患者腰椎(L1～4)、股骨近端(颈部Neck、大粗隆Troch、合计Total)骨密度(BMD),同时用肺功能仪测定肺功能,血气分析仪测量动脉血气分析,以及生化、血钙等检查。结果COPD组的BMD值与对照组相比显著降低(P<0.001),COPD患者骨密度与一秒钟用力呼气量(FEV1%)均呈显著正相关(P<0.001)。昆明地区老年COPD组骨密度低于对照组。结论老年COPD患者骨密度检查能及早发现骨质疏松。低氧血症可能是老年COPD患者合并OP的主要危险因素。Objective To examine the relevance between chronic obstructive pulmonary disease （COPD）and osteoporosis by measurement of bone density （BMD）,lung function and the change of arterial blood gas anlysis of the senior in kunming region. Methods BMD of 32 old male patients with COPD was measured by dual-energy X-ray absorptiometry （DEXA）. Measuring the wast vertebra （L1-4） the close of cuboideum head ervical and troch total BMD. At the same time lung function was measured by lung function instrument,arterial blood gas analysis was measured by instrument,and analy sis the chemical. Ca^2＋ of blood etc. Results In COPD sroup BMD levels were much lower than those in control （P〈0.001）, the FEVI% in COPD group were higher than those control （P〈0.001）. BMD in COPD patients were lower than that in controls. Conclusion We can find early Op by measure the BMD. Blood-meionectiv might be the important factor which can result OP in the senior who have COPD ditase.

关 键 词：COPD 低氧血症 骨质疏松 骨密度 

分 类 号：R563.9[医药卫生—呼吸系统] R580[医药卫生—内科学]