尿中MDMA和MDA的三氟乙酰化-GC/MS/MS分析法  

Determination of MDA and MDMA by TFA Derivatization-GC/MS/MS

作　　者：于晓娟[1] 李国平[1] 

机构地区：[1]辽宁警官高等专科学校

出　　处：《光谱实验室》2009年第4期1051-1053,共3页Chinese Journal of Spectroscopy Laboratory

基　　金：辽宁省教育万基金资助项目

摘　　要：建立了尿中MDMA和MDA的、用环己烷提取的、三氟乙酸酐衍生化的、GC/MS/MS检测的分析方法。方法操作简便快速,检测MDMA最灵敏的检出限为4ng/mL,检测MDA最灵敏的检出限为2.0ng/mL。方法的回收率为73%—94%,具有较好的线性关系。The methods for analysis of MDMA and MDA in urine by cyclohexane extraction and various acyl erivafization and determination with GC/MS/MS were developed.These methods were rapid and simple.The limits of detection（LOD）of most of the methods were below 10ng/mL.The LOD of MDMA was 4 ng/mL.LOD of MDA was 2ng/mL.Several more sensitive methods were selected to examine the linearity and recovery.The results were satisfactory.

关 键 词：致幻性安非他明类药物 衍生化 气相色谱/质谱分析 尿 

分 类 号：O657.63[理学—分析化学]